PYCR1

Gene Symbol PYCR1
Entrez Gene 5831
Alt Symbol ARCL2B, ARCL3B, P5C, P5CR, PIG45, PP222, PRO3, PYCR
Species Human
Gene Type protein-coding
Description pyrroline-5-carboxylate reductase 1
Other Description P5C reductase 1|proliferation-inducing protein 45|pyrroline-5-carboxylate reductase 1, mitochondrial
Swissprots Q6FHI4 Q9HBQ4 B4DMU0 A6NFM2 P32322 Q96DI6
Accessions ADG28674 EAW89717 EAW89718 EAW89719 EAW89720 EAW89721 EAW89722 EAW89723 EAW89724 EAW89725 EAW89726 P32322 AA026075 AF218000 AAG17242 AK225879 AK297627 BAG60002 AK303852 BAH14067 AL561248 AY513285 AAT08038 BC001504 AAH01504 BC022244 AAH22244 BC071842 AAH71842 CR541769 CAG46568 DA521426 HQ154643 ADU15815 HQ154644 ADU15816 HQ447821 ADQ32305 JF432573 ADZ15790 M77836 AAA36407 XM_005256381 XP_005256438 XM_011523583 XP_011521885 XM_011523584 XP_011521886 XM_011523585 XP_011521887 NM_001282279 NP_001269208 NM_001282280 NP_001269209 NM_001282281 NP_001269210 NM_006907 NP_008838 NM_153824 NP_722546
Function Housekeeping enzyme that catalyzes the last step in proline biosynthesis. Can utilize both NAD and NADP, but has higher affinity for NAD. Involved in the cellular response to oxidative stress. {ECO:0000269|PubMed:16730026, ECO:0000269|PubMed:19648921}.
Subcellular Location Mitochondrion {ECO:0000269|PubMed:19648921}.
Top Pathways Arginine and proline metabolism, Biosynthesis of amino acids

P5CR CRISPR/Cas9 KO Plasmid (h) - sc-410971 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

P5CR HDR Plasmid (h) - sc-410971-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

P5CR Double Nickase Plasmid (h) - sc-410971-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

P5CR Double Nickase Plasmid (h2) - sc-410971-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

P5CR CRISPR Activation Plasmid (h) - sc-410971-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

P5CR CRISPR Activation Plasmid (h2) - sc-410971-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

P5CR Lentiviral Activation Particles (h) - sc-410971-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

P5CR Lentiviral Activation Particles (h2) - sc-410971-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

P5CR siRNA (h) - sc-93710 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

P5CR shRNA Plasmid (h) - sc-93710-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

P5CR shRNA (h) Lentiviral Particles - sc-93710-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU114861 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN17767 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17767 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR06989 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr06989

PYCR1 siRNA (Human) - CRH3943 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PYCR1 (NM_006907.2) - SHH387376 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human PYCR1(NM_153824.1) - SHR155820 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human PYCR1(NM_006907.2) - SHR155874 from Creative biogene

Category siRNA
Species Reactivities Human

PYCR1 shRNA Plasmid (Human) - CHH3943 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PYCR1 miRNA 3'UTR clone - MiUTR1H-08520 from Creative biogene

Species Reactivities Human

PYCR1 miRNA 3'UTR clone - MiUTR1H-08521 from Creative biogene

Species Reactivities Human
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