SPTSSB

Gene Symbol SPTSSB
Entrez Gene 165679
Alt Symbol ADMP, C3orf57, SSSPTB
Species Human
Gene Type protein-coding
Description serine palmitoyltransferase, small subunit B
Other Description androgen down regulated in mouse prostate|likely ortholog of androgen down regulated gene expressed in mouse prostate|serine palmitoyltransferase small subunit B|small subunit of serine palmitoyltransferase B
Swissprots D3DNM8 Q0P5S6 Q8NFR3 B2R5D3
Accessions EAW78615 EAW78616 EAW78617 Q8NFR3 AF458592 AAM49720 AK123348 BAC85589 AK312144 BAG35080 BC037817 BC065208 AAH65208 BC071875 AAH71875 BC107756 AAI07757 BC126236 AAI26237 BC130565 BU950276 BU950567 XM_011512481 XP_011510783 XM_011512482 XP_011510784 NM_145035 NM_001040100 NP_001035189
Function Stimulates the activity of serine palmitoyltransferase (SPT). The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference, complexes with this subunit showing a clear preference for longer acyl-CoAs. The SPTLC1-SPTLC2-SPTSSB complex shows a strong preference for C18-CoA substrate, while the SPTLC1-SPTLC3-SPTSSB isozyme displays an ability to use a broader range of acyl-CoAs, without apparent preference. May play a role in signal transduction. {ECO:0000269|PubMed:19416851}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Tissue Specificity Expression is seen predominantly in the prostate epithelium with weaker expression in the fibroblasts and endothelial cells. {ECO:0000269|PubMed:15777716}.

Human SPTSSB cDNA clone(NM_001040100.1) - CDFH018586 from Creative Biomart

Species Human
Accession NM_001040100.1

Human SPTSSB cDNA clone(NM_001040100.1) - CDFH018587 from Creative Biomart

Species Human
Accession NM_001040100.1

Human SPTSSB ORF Clone(NM_001040100.1) - CDCR343749 from Creative Biomart

Species Human
Accession NM_001040100.1

Human SPTSSB ORF Clone(NM_001040100.1) - CDCR343750 from Creative Biomart

Species Human
Accession NM_001040100.1

Human SPTSSB ORF Clone(NM_001040100.1) - CDCR344021 from Creative Biomart

Species Human
Accession NM_001040100.1

Human SPTSSB Gene cDNA Clone (full-length ORF Clone) - HG16210-G from Sino Biological

Species Human
Accession NM_001040100.1

Human SPTSSB Gene cDNA Clone (full-length ORF Clone), expression ready, untagged - HG16210-UT from Sino Biological

Species Human
Accession NM_001040100.1

Human SPTSSB natural ORF mammalian expression plasmid, C-Flag tag - HG16210-CF from Sino Biological

Species Human
Accession NM_001040100.1

Human SPTSSB natural ORF mammalian expression plasmid, N-Myc tag - HG16210-NM from Sino Biological

Species Human
Accession NM_001040100.1

Human SPTSSB ORF Clone(NM_001040100.1) - CDCR343749 from Creative biogene

Species Human

Human SPTSSB ORF Clone (BC065208) - CDCS419634 from Creative biogene

Species Human
Accession Q6ZWB5

Human SPTSSB cDNA Clone(NM_001040100.1) - CDFH018586 from Creative biogene

Species Human

Human SPTSSB cDNA Clone(NM_001040100.1) - CDFH018587 from Creative biogene

Species Human
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