SPTSSB

Gene Symbol SPTSSB
Entrez Gene 165679
Alt Symbol ADMP, C3orf57, SSSPTB
Species Human
Gene Type protein-coding
Description serine palmitoyltransferase, small subunit B
Other Description androgen down regulated in mouse prostate|likely ortholog of androgen down regulated gene expressed in mouse prostate|serine palmitoyltransferase small subunit B|small subunit of serine palmitoyltransferase B
Swissprots D3DNM8 Q0P5S6 Q8NFR3 B2R5D3
Accessions EAW78615 EAW78616 EAW78617 Q8NFR3 AF458592 AAM49720 AK123348 BAC85589 AK312144 BAG35080 BC037817 BC065208 AAH65208 BC071875 AAH71875 BC107756 AAI07757 BC126236 AAI26237 BC130565 BU950276 BU950567 XM_011512481 XP_011510783 XM_011512482 XP_011510784 NM_145035 NM_001040100 NP_001035189
Function Stimulates the activity of serine palmitoyltransferase (SPT). The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference, complexes with this subunit showing a clear preference for longer acyl-CoAs. The SPTLC1-SPTLC2-SPTSSB complex shows a strong preference for C18-CoA substrate, while the SPTLC1-SPTLC3-SPTSSB isozyme displays an ability to use a broader range of acyl-CoAs, without apparent preference. May play a role in signal transduction. {ECO:0000269|PubMed:19416851}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Tissue Specificity Expression is seen predominantly in the prostate epithelium with weaker expression in the fibroblasts and endothelial cells. {ECO:0000269|PubMed:15777716}.

ADMP CRISPR/Cas9 KO Plasmid (h) - sc-414886 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ADMP HDR Plasmid (h) - sc-414886-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ADMP Double Nickase Plasmid (h) - sc-414886-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ADMP Double Nickase Plasmid (h2) - sc-414886-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ADMP CRISPR Activation Plasmid (h) - sc-414886-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ADMP CRISPR Activation Plasmid (h2) - sc-414886-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ADMP Lentiviral Activation Particles (h) - sc-414886-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ADMP Lentiviral Activation Particles (h2) - sc-414886-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ADMP siRNA (h) - sc-78035 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ADMP shRNA Plasmid (h) - sc-78035-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ADMP shRNA (h) Lentiviral Particles - sc-78035-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU118191 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN4910 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4910 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

SPTSSB siRNA (Human) - CRJ6032 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SPTSSB - MBS8238327 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human C3orf57 (NM_001040100.1) - SHH251717 from Creative biogene

Category siRNA
Species Reactivities Human

SPTSSB shRNA Plasmid (Human) - CHJ6032 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SPTSSB miRNA 3'UTR clone - MiUTR1H-01396 from Creative biogene

Species Reactivities Human
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