Gene Symbol | Fasl |
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Entrez Gene | 14103 |
Alt Symbol | APT1LG1, CD178, CD95-L, CD95L, Fas-L, Faslg, Tnfsf6, gld |
Species | Mouse |
Gene Type | protein-coding |
Description | Fas ligand (TNF superfamily, member 6) |
Other Description | CD95 ligand|Fas antigen ligand|generalized lymphoproliferative disease|tumor necrosis factor ligand superfamily member 6 |
Swissprots | P41047 Q61217 Q9R1F2 |
Accessions | AAD14773 ABI24108 ABI24109 ABI24110 EDL39311 P41047 AF119335 AAD52106 AF288572 AAG60016 AK040139 BAC30520 AK141268 BAE24625 BC052866 AAH52866 DQ846747 ABI24111 S76752 AAB33780 U06948 AAA17800 U10984 AAA19778 U58995 AAB02915 XM_006496653 XP_006496716 XM_006496654 XP_006496717 NM_001205243 NP_001192172 NM_010177 NP_034307 |
Function | Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects (By similarity). {ECO:0000250}. |
Subcellular Location | Tumor necrosis factor ligand superfamily member 6, soluble form: Secreted. Note=May be released into the extracellular fluid, probably by cleavage form the cell surface. |
Top Pathways | Chagas disease (American trypanosomiasis), PI3K-Akt signaling pathway, Non-alcoholic fatty liver disease (NAFLD), Herpes simplex infection, Proteoglycans in cancer |
Recombinant Mouse Fas Ligand/TNFSF6 - 6128-SA-025 from R&D Systems
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Recombinant Mouse Fas Ligand/TNFSF6, CF - 6128-SA-025/CF from R&D Systems
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sFas Ligand, Human, Recombinant - 28-10129 from ARP American Research Products
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Fasl fusion protein - ag0893 from Proteintech Group
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Recombinant Mouse Fas Ligand (TNF superfamily, member 6) - Fasl-482M from Creative Biomart
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Recombinant Mouse Fas Ligand (TNF Superfamily, Member 6) - Fasl-1736M from Creative Biomart
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Recombinant Factor Related Apoptosis Ligand (FASL) - RPA031Mu01 from Cloud-clone
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Recombinant Factor Related Apoptosis Ligand (FASL) - RPA031Mu02 from Cloud-clone
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Recombinant Mouse Tumor necrosis factor ligand superfamily member 6(Faslg) - CSB-YP008434MO CSB-EP008434MO CSB-BP008434MO CSB-MP008434MO from Cusabio
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Recombinant Mouse Fas Ligand/TNFSF6 Protein, CF - 6128-SA/CF from R&D Systems
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Recombinant Mouse Fas Ligand/TNFSF6 Protein - 6128-SA from R&D Systems
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FAS-L, Peptide - MBS443039 from MyBioSource
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FasL, Peptide - MBS843838 from MyBioSource
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Mouse Fas Ligand / FASLG / CD95L Protein (His Tag) - 50854-M07Y-200 from Sino Biological
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FASL Recombinant Protein (OPCD03095) - OPCD03095 from Aviva Systems Biology
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Mouse Fas Ligand / FASLG / CD95L Protein (His Tag) - 50854-M07Y from ABclonal
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Recombinant Mouse Faslg Protein, His-tagged - Faslg-372M from Creative Biomart
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