| Gene Symbol |
ARHGEF6
|
| Entrez Gene |
9459
|
| Alt Symbol |
COOL2, Cool-2, MRX46, PIXA, alpha-PIX, alphaPIX
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
|
| Other Description |
PAK-interacting exchange factor alpha|PAK-interacting exchange factor, alpha|Rac/Cdc42 guanine exchange factor (GEF) 6|rac/Cdc42 guanine nucleotide exchange factor 6|rho guanine nucleotide exchange factor 6
|
| Swissprots |
Q86XH0 Q5JQ66 Q15396 A6NMW9 Q15052 B1AL37 Q7Z3W1 A8K6S7
|
| Accessions |
EAW88460 EAW88461 Q15052 AF207831 AAG27169 AK129909 AK291742 BAF84431 AK294929 BAH11929 AK295709 BAH12163 AK299861 BAH13153 BC033768 AAH33768 BC039856 AAH39856 BC043505 AAH43505 BE243825 BX537390 CAD97632 D13631 BAA02796 D25304 BAA04985 XM_005262499 XP_005262556 XM_005262501 XP_005262558 XM_011531412 XP_011529714 XM_011531413 XP_011529715 XM_011531414 XP_011529716 XM_011531415 XP_011529717 XM_011531416 XP_011529718 XM_011531417 XP_011529719 NM_001306177 NP_001293106 NM_004840 NP_004831
|
| Function |
Acts as a RAC1 guanine nucleotide exchange factor (GEF).
|
| Subcellular Location |
Cell projection, lamellipodium {ECO:0000250}.
|
| Tissue Specificity |
Ubiquitous.
|
| Top Pathways |
Pancreatic cancer, Regulation of actin cytoskeleton
|