ARHGEF6

Gene Symbol ARHGEF6
Entrez Gene 9459
Alt Symbol COOL2, Cool-2, MRX46, PIXA, alpha-PIX, alphaPIX
Species Human
Gene Type protein-coding
Description Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
Other Description PAK-interacting exchange factor alpha|PAK-interacting exchange factor, alpha|Rac/Cdc42 guanine exchange factor (GEF) 6|rac/Cdc42 guanine nucleotide exchange factor 6|rho guanine nucleotide exchange factor 6
Swissprots Q86XH0 Q5JQ66 Q15396 A6NMW9 Q15052 B1AL37 Q7Z3W1 A8K6S7
Accessions EAW88460 EAW88461 Q15052 AF207831 AAG27169 AK129909 AK291742 BAF84431 AK294929 BAH11929 AK295709 BAH12163 AK299861 BAH13153 BC033768 AAH33768 BC039856 AAH39856 BC043505 AAH43505 BE243825 BX537390 CAD97632 D13631 BAA02796 D25304 BAA04985 XM_005262499 XP_005262556 XM_005262501 XP_005262558 XM_011531412 XP_011529714 XM_011531413 XP_011529715 XM_011531414 XP_011529716 XM_011531415 XP_011529717 XM_011531416 XP_011529718 XM_011531417 XP_011529719 NM_001306177 NP_001293106 NM_004840 NP_004831
Function Acts as a RAC1 guanine nucleotide exchange factor (GEF).
Subcellular Location Cell projection, lamellipodium {ECO:0000250}.
Tissue Specificity Ubiquitous.
Top Pathways Pancreatic cancer, Regulation of actin cytoskeleton

Cool2/αPix (C23D2) Rabbit mAb - 4573 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone C23D2
Western blot analysis of extracts from various cell types using Cool2/αPix (C23D2) Rabbit mAb.

αPIX (C-14) - sc-10925 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

αPIX (H-80) - sc-368118 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

αPIX (Q-20) - sc-10927 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
αPIX (Q-20): sc-10927. Immunoperoxidase staining of formalin fixed, paraffin-embedded human lower stomach tissue showing cytoplasmic staining of glandular cells.

Anti-ARHGEF6 antibody - ab199124 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue labeling ARHGEF6 with ab199124 at 1/70 dilution.

Anti-ARHGEF6 antibody - ab91562 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab91562 at 1 µg/ml detecting ARHGEF6 in Jurkat whole cell lysate by WB following IP. Lane 1; IP with ab91562 at 10 µg/mg of lysate. Lane 2; IP with an antibody which recognizes an downstream epitope of ARHGEF6. Lane 3; control IgG. In each case, 1 mg of lysate was used for IP and 20% of the IP was loaded. Detection utilised ECL with a 10 second exposure.

Anti-ARHGEF6 antibody - ab69888 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-ARHGEF6 antibody (ab69888) at 1/500 dilutionLane 1 : ARHGEF6 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-ARHGEF6 antibody - ab91572 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Detection of ARHGEF6 by Western Blot of Immunprecipitate. anti-ARHGEF6, at 1 µg/ml, staining ARHGEF6 in Jurkat whole cell lysate immunoprecipitated using ab91572 at 10 µg/mg lysate (1 mg/IP; 20% of IP loaded/lane). Detection: Chemiluminescence with exposure time of 10 seconds.

Anti-ARHGEF6 antibody [EPR11700(2)] - ab184569 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR11700(2)
All lanes : Anti-ARHGEF6 antibody [EPR11700(2)] (ab184569) at 1/10000 dilutionLane 1 : Raji cell lysateLane 2 : Jurkat cell lysateLane 3 : HeLa cell lysateLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugate at 1/1000 dilution

Anti-ARHGEF6 Antibody (aa614-641, Biotin) - LS-C251697 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ARHGEF6 Antibody (aa614-641, APC) - LS-C251696 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ARHGEF6 Antibody (aa614-641, Azide-free, HRP) - LS-C251699 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ARHGEF6 Antibody (aa614-641, AP) - LS-C251695 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ARHGEF6 Antibody (aa614-641, FITC) - LS-C251698 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ARHGEF6 Antibody (aa614-641, PE) - LS-C251700 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ARHGEF6 Antibody (aa50-100) - LS-C289290 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ARHGEF6 Antibody (aa726-776) - LS-C289292 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ARHGEF6 Antibody (aa61-175) - LS-C306341 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-ARHGEF6 Antibody - LS-C306340 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-ARHGEF6 Antibody - LS-C309504 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ARHGEF6 Antibody (aa613-641) - LS-C319588 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ARHGEF6 Antibody (aa614-641) - LS-C156483 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
ARHGEF6 Antibody western blot of K562 cell line lysates (35 ug/lane). The ARHGEF6 antibody detected the ARHGEF6 protein (arrow).

ARHGEF6 Antibody - NBP1-89124 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ARHGEF6 Antibody [NBP1-89124] - Analysis in human cell line HL-60.

ARHGEF6 Antibody (2E5) - H00009459-M02 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2E5
Western Blot: ARHGEF6 Antibody (2E5) [H00009459-M02] - Analysis of ARHGEF6 expression in transfected 293T cell line by ARHGEF6 monoclonal antibody (M02), clone 2E5.Lane 1: ARHGEF6 transfected lysate (Predicted MW: 87.5 KDa).Lane 2: Non-transfected lysate.

ARHGEF6 Antibody - NBP1-30451 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunoprecipitation: ARHGEF6 Antibody [NBP1-30451] - Detection of Human ARHGEF6 Whole cell lysate (1 mg for IP, 20% of IP loaded) from Jurkat cells. Antibodies: Affinity purified rabbit anti-ARHGEF6 antibody NBP1-30451 used for IP at 10 mcg/mg lysate. ARHGEF6 was also immunoprecipitated by rabbit anti-ARHGEF6 antibody NBP1-30450, which recognizes an upstream epitope.
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