Gene Symbol | ARHGEF6 |
---|---|
Entrez Gene | 9459 |
Alt Symbol | COOL2, Cool-2, MRX46, PIXA, alpha-PIX, alphaPIX |
Species | Human |
Gene Type | protein-coding |
Description | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 |
Other Description | PAK-interacting exchange factor alpha|PAK-interacting exchange factor, alpha|Rac/Cdc42 guanine exchange factor (GEF) 6|rac/Cdc42 guanine nucleotide exchange factor 6|rho guanine nucleotide exchange factor 6 |
Swissprots | Q86XH0 Q5JQ66 Q15396 A6NMW9 Q15052 B1AL37 Q7Z3W1 A8K6S7 |
Accessions | EAW88460 EAW88461 Q15052 AF207831 AAG27169 AK129909 AK291742 BAF84431 AK294929 BAH11929 AK295709 BAH12163 AK299861 BAH13153 BC033768 AAH33768 BC039856 AAH39856 BC043505 AAH43505 BE243825 BX537390 CAD97632 D13631 BAA02796 D25304 BAA04985 XM_005262499 XP_005262556 XM_005262501 XP_005262558 XM_011531412 XP_011529714 XM_011531413 XP_011529715 XM_011531414 XP_011529716 XM_011531415 XP_011529717 XM_011531416 XP_011529718 XM_011531417 XP_011529719 NM_001306177 NP_001293106 NM_004840 NP_004831 |
Function | Acts as a RAC1 guanine nucleotide exchange factor (GEF). |
Subcellular Location | Cell projection, lamellipodium {ECO:0000250}. |
Tissue Specificity | Ubiquitous. |
Top Pathways | Pancreatic cancer, Regulation of actin cytoskeleton |
αPIX CRISPR/Cas9 KO Plasmid (h) - sc-404891 from Santa Cruz Biotechnology
|
||||||||
αPIX HDR Plasmid (h) - sc-404891-HDR from Santa Cruz Biotechnology
|
||||||||
αPIX Double Nickase Plasmid (h) - sc-404891-NIC from Santa Cruz Biotechnology
|
||||||||
αPIX Double Nickase Plasmid (h2) - sc-404891-NIC-2 from Santa Cruz Biotechnology
|
||||||||
αPIX CRISPR Activation Plasmid (h) - sc-404891-ACT from Santa Cruz Biotechnology
|
||||||||
αPIX CRISPR Activation Plasmid (h2) - sc-404891-ACT-2 from Santa Cruz Biotechnology
|
||||||||
αPIX Lentiviral Activation Particles (h) - sc-404891-LAC from Santa Cruz Biotechnology
|
||||||||
αPIX Lentiviral Activation Particles (h2) - sc-404891-LAC-2 from Santa Cruz Biotechnology
|
||||||||
αPIX siRNA (h) - sc-39146 from Santa Cruz Biotechnology
|
||||||||
αPIX shRNA Plasmid (h) - sc-39146-SH from Santa Cruz Biotechnology
|
||||||||
αPIX shRNA (h) Lentiviral Particles - sc-39146-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU133681 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN3462 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3462 from Sigma-Aldrich
|
||||||||
ARHGEF6 siRNA (Human) - CRH6276 from Cohesion Biosciences
|
||||||||
ARHGEF6 - MBS8216663 from MyBioSource
|
||||||||
shRNA set against Human ARHGEF6 (NM_004840.2) - SHH239890 from Creative biogene
|
||||||||
shRNA set against Human ARHGEF6(NM_004840.2) - SHG071395 from Creative biogene
|
||||||||
Human ARHGEF6 siRNA - orb266778 from Biorbyt
|
||||||||
ARHGEF6 shRNA Plasmid (Human) - CHH6276 from Cohesion Biosciences
|
||||||||
ARHGEF6 miRNA 3'UTR clone - MiUTR1H-00546 from Creative biogene
|