FHL2

Gene Symbol	FHL2
Entrez Gene	2274
Alt Symbol	AAG11, DRAL, FHL-2, SLIM-3, SLIM3
Species	Human
Gene Type	protein-coding
Description	four and a half LIM domains 2
Other Description	LIM domain protein DRAL|aging-associated gene 11|down-regulated in rhabdomyosarcoma LIM protein|four and a half LIM domains protein 2|skeletal muscle LIM-protein 3
Swissprots	Q13229 Q2I5I4 Q14192 Q9P294 Q13644 Q5TM15
Accessions	AAY14896 AAY15012 BAA92253 EAX01758 EAX01759 EAX01760 Q14192 AA758053 AB158503 BAD69710 AK097756 AK313841 BAG36573 AY634685 AAV35468 BC012742 AAH12742 BC014397 AAH14397 BC036085 BC093049 AAH93049 BI092736 BM836767 BP257466 BT006960 AAP35606 BX340370 CB989635 CF552311 CR457437 CAG33718 CR936682 CR936799 DQ266432 ABB73038 DQ307067 ABC25549 DQ896335 ABM87334 EU176424 ABW03875 JQ313902 AFH75080 L42176 AAA85333 U29332 AAC52073 U60117 AAC50794 XM_005263902 XP_005263959 XM_005263906 XP_005263963 XM_011510798 XP_011509100 XM_011510799 XP_011509101 XM_011510800 XP_011509102 NM_001039492 NP_001034581 NM_001450 NP_001441 NM_201555 NP_963849 NM_201557 NP_963851 NM_201556
Function	May function as a molecular transmitter linking various signaling pathways to transcriptional regulation. Negatively regulates the transcriptional repressor E4F1 and may function in cell growth. Inhibits the transcriptional activity of FOXO1 and its apoptotic function by enhancing the interaction of FOXO1 with SIRT1 and FOXO1 deacetylation. {ECO:0000269|PubMed:15692560, ECO:0000269|PubMed:16652157, ECO:0000269|PubMed:18853468}.
Subcellular Location	Cytoplasm. Nucleus.
Tissue Specificity	Expressed in skeletal muscle and heart. {ECO:0000269|PubMed:11813260}.
Top Pathways	Osteoclast differentiation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human FHL2 full length protein - ab132098 from Abcam Category Protein Source Wheat germ Species Human

Human FHL2 full length protein - ab187462 from Abcam Category Protein Source E. coli Species Human

Human RALA+RALB peptide - ab42531 from Abcam Category Peptide

FHL2 Antibody Blocking Peptide - LS-E25693 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

FHL2 Antibody Blocking Peptide - LS-E12241 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

FHL2 Antibody Blocking Peptide - LS-E18227 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

FHL2 Recombinant Protein - H00002274-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

FHL2 blocking peptide - GTX15715-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat, Bovine

FHL2 peptide - orb108406 from Biorbyt Category Peptide Prices $374.00 Sizes 50 μg

FHL2 Blocking Peptide - 33R-7909 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

FHL2 protein (His tag) - 80R-3992 from Fitzgerald Category Protein Prices $375.00 Sizes 100 µg Source E.coli

FHL2 Blocking Peptide - abx062620 from Abbexa Category Peptide Species Human, Mouse, Rat, Bovine

FHL2 Peptide - AC21-0524-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

FHL2 / SLIM3 (1-279, His-tag) - AR51677PU-N from Acris Antibodies Category Protein Prices $1,010.00 Sizes 500 µg Source E. coli Species Human

FHL2 / SLIM3 (1-279, His-tag) - AR51677PU-S from Acris Antibodies Category Protein Prices $410.00 Sizes 100 µg Source E. coli Species Human

FHL2 / SLIM3 - H00002274-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

FHL2 / SLIM3 - H00002274-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

FHL2 / SLIM3 control peptide - AP05258CP-N from Acris Antibodies Category Peptide Prices $205.00 Sizes 50 µg

FHL2 Peptide - 45-592P from ProSci Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse

FHL2 fusion protein - ag1378 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human four and a half LIM domains 2, His-tagged - FHL2-634H from Creative Biomart Category Protein Source E.coli Species Human

FHL2 Blocking Peptide - CBP1426 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Bovine

FHL2 Peptide - BS60427P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human Four and a half LIM domains protein 2(FHL2) - CSB-YP617906HU CSB-EP617906HU CSB-BP617906HU CSB-MP617906HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

FHL2, 1-279aa, Human, His tag, E.coli (Denatured) - ATGP2857 from ATGen Category Protein Prices $105.00, $320.00, $960.00 Sizes 20 µg, 100 µg, 500 µg Species Human

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