MKKS

Gene Symbol MKKS
Entrez Gene 8195
Alt Symbol BBS6, HMCS, KMS, MKS
Species Human
Gene Type protein-coding
Description McKusick-Kaufman syndrome
Other Description Bardet-Biedl syndrome 6 protein|McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin
Swissprots Q9NPJ1 D3DW18 A8K7B0
Accessions EAX10343 EAX10344 EAX10345 Q9NPJ1 AF075024 AF221992 AAF73872 AF221993 AAF73873 AF275813 AAG23823 AK025741 BAB15230 AK291925 BAF84614 AK296439 BAH12355 AL157427 CAB75652 AM393018 CAL37896 BC009180 BC013287 BC028973 AAH28973 BM019257 DA209180 NM_018848 NP_061336 NM_170784 NP_740754 NR_072977
Function Probable molecular chaperone. Assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. May play a role in protein processing in limb, cardiac and reproductive system development. May play a role in cytokinesis. {ECO:0000269|PubMed:20080638}.
Subcellular Location Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytosol. Note=The majority of the protein resides within the pericentriolar material (PCM), a proteinaceous tube surrounding centrioles. During interphase, the protein is confined to the lateral surfaces of the PCM but during mitosis it relocalizes throughout the PCM and is found at the intercellular bridge. The MKSS protein is highly mobile and rapidly shuttles between the cytosol and centrosome.
Tissue Specificity Widely expressed in adult and fetal tissues.

BBS6 (E-14) - sc-49798 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
BBS6 (E-14): sc-49798. Western blot analysis of BBS6 expression in non-transfected 293T: sc-117752 (A), human BBS6 transfected 293T: sc-113970 (B) and HeLa (C) whole cell lysates.

BBS6 (F-8) - sc-390077 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
BBS6 (F-8): sc-390077. Western blot analysis of BBS6 expression in MIA PaCa-2 (A), Jurkat (B), SK-LMS-1 (C), IMR-32 (D), WI 38 (E) and NTERA-2 cl.D1 (F) whole cell lysates.

BBS6 (C-20) - sc-49797 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

BBS6 (H-300) - sc-134456 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

BBS6 (N-14) - sc-49799 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
BBS6 (N-14): sc-49799. Western blot analysis of BBS6 expression in non-transfected: sc-117752 (A) and human BBS6 transfected: sc-113970 (B) 293T whole cell lysates.

Anti-MKKS antibody - ab103816 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-MKKS antibody (ab103816) at 1/500 dilution + A431 Cell Lysate at 50 µg

Anti-MKKS antibody - ab123980 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-MKKS antibody (ab123980) at 1/100 dilution + U251 cell line lysate at 35 µg

Anti-MKKS antibody - ab167295 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-MKKS antibody (ab167295) at 1 µg/mlLane 1 : MKKS transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.

Anti-MKKS antibody - C-terminal - ab198210 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin embedded human brain tissue labeling MKKS with ab198210 at a 1/50 dilution.

Anti-MKKS Antibody (aa408-437, APC) - LS-C246509 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MKKS Antibody (aa408-437, AP) - LS-C246508 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MKKS Antibody (aa408-437, PE) - LS-C237671 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MKKS Antibody (aa408-437, Biotin) - LS-C246510 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MKKS Antibody (aa408-437, Azide-free, HRP) - LS-C248824 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MKKS Antibody (aa408-437, FITC) - LS-C246511 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MKKS Antibody (aa407-438) - LS-C323014 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MKKS Antibody - LS-C310983 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MKKS Antibody (aa408-437) - LS-C164209 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
MKKS Antibody western blot of U251 cell line lysates (35 ug/lane). The MKKS antibody detected the MKKS protein (arrow).

MKKS Antibody - NBP1-92123 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: MKKS Antibody [NBP1-92123] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp

MKKS Antibody - NBP1-92122 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: MKKS Antibody [NBP1-92122] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Human cell line RT-4

MKKS Antibody - H00008195-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: MKKS Antibody [H00008195-B01] - analysis of MKKS expression in transfected 293T cell line by MKKS MaxPab polyclonal antibody. Lane 1: MKKS transfected lysate (62.7 KDa). Lane 2: Non-transfected lysate.

MKKS Antibody - H00008195-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: MKKS Antibody [H00008195-D01P] - Analysis of MKKS expression in A-431.

MKKS Antibody - H00008195-D01 from Novus Biologicals

Prices $399.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

MKKS Antibody - H00008195-B01P from Novus Biologicals

Prices $349.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

BBS6 Polyclonal Antibody - bs-7754R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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