MKKS

Gene Symbol	MKKS
Entrez Gene	8195
Alt Symbol	BBS6, HMCS, KMS, MKS
Species	Human
Gene Type	protein-coding
Description	McKusick-Kaufman syndrome
Other Description	Bardet-Biedl syndrome 6 protein|McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin
Swissprots	Q9NPJ1 D3DW18 A8K7B0
Accessions	EAX10343 EAX10344 EAX10345 Q9NPJ1 AF075024 AF221992 AAF73872 AF221993 AAF73873 AF275813 AAG23823 AK025741 BAB15230 AK291925 BAF84614 AK296439 BAH12355 AL157427 CAB75652 AM393018 CAL37896 BC009180 BC013287 BC028973 AAH28973 BM019257 DA209180 NM_018848 NP_061336 NM_170784 NP_740754 NR_072977
Function	Probable molecular chaperone. Assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. May play a role in protein processing in limb, cardiac and reproductive system development. May play a role in cytokinesis. {ECO:0000269|PubMed:20080638}.
Subcellular Location	Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytosol. Note=The majority of the protein resides within the pericentriolar material (PCM), a proteinaceous tube surrounding centrioles. During interphase, the protein is confined to the lateral surfaces of the PCM but during mitosis it relocalizes throughout the PCM and is found at the intercellular bridge. The MKSS protein is highly mobile and rapidly shuttles between the cytosol and centrosome.
Tissue Specificity	Widely expressed in adult and fetal tissues.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human MKKS full length protein - ab159959 from Abcam Category Protein Source Wheat germ Species Human

Human MKKS protein fragment - ab159960 from Abcam Category Protein Source Wheat germ Species Human

MKKS Antibody Blocking Peptide - LS-E4064 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human MKKS Protein - H00008195-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human MKKS Protein - H00008195-Q01 from Novus Biologicals Category Protein Prices $250.00 Sizes 2 µg Source Wheat Germ Species Human

MKKS-Antibody-C-term-Blocking-Peptide - BP16289b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

MKKS - H00008195-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

MKKS - H00008195-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

MKKS - H00008195-Q01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

MKKS - H00008195-Q01-10 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

MKKS - H00008195-Q01-25 from Acris Antibodies Category Protein Prices $520.00 Sizes 25 µg Species Human

BBS6 fusion protein - ag3785 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human MKKS - MKKS-726H from Creative Biomart Category Protein Source Mammalian Cells Species Human

Recombinant Human McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin(MK - CSB-YP878846HU CSB-EP878846HU CSB-BP878846HU CSB-MP878846HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

BBS6 Protein - abx164887 from Abbexa Category Protein Species Human, Mouse, Rat

MKKS Protein - NBP1-92123PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

MKKS Recombinant Protein Antigen - NBP1-92122PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

MKKS Peptide, Human - M34GP09542H from Creative Peptides Category Peptide Source Synthetic. Species Human

McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin (MKKS), Recombinant Protein - MBS1295575 from MyBioSource Category Protein Prices $1,370.00, $1,370.00, $1,585.00, $1,585.00, $2,275.00, $2,275.00, $2,740.00, $2,740.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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