MKKS

Gene Symbol MKKS
Entrez Gene 8195
Alt Symbol BBS6, HMCS, KMS, MKS
Species Human
Gene Type protein-coding
Description McKusick-Kaufman syndrome
Other Description Bardet-Biedl syndrome 6 protein|McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin
Swissprots Q9NPJ1 D3DW18 A8K7B0
Accessions EAX10343 EAX10344 EAX10345 Q9NPJ1 AF075024 AF221992 AAF73872 AF221993 AAF73873 AF275813 AAG23823 AK025741 BAB15230 AK291925 BAF84614 AK296439 BAH12355 AL157427 CAB75652 AM393018 CAL37896 BC009180 BC013287 BC028973 AAH28973 BM019257 DA209180 NM_018848 NP_061336 NM_170784 NP_740754 NR_072977
Function Probable molecular chaperone. Assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. May play a role in protein processing in limb, cardiac and reproductive system development. May play a role in cytokinesis. {ECO:0000269|PubMed:20080638}.
Subcellular Location Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytosol. Note=The majority of the protein resides within the pericentriolar material (PCM), a proteinaceous tube surrounding centrioles. During interphase, the protein is confined to the lateral surfaces of the PCM but during mitosis it relocalizes throughout the PCM and is found at the intercellular bridge. The MKSS protein is highly mobile and rapidly shuttles between the cytosol and centrosome.
Tissue Specificity Widely expressed in adult and fetal tissues.

BBS6 CRISPR/Cas9 KO Plasmid (h) - sc-416977 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

BBS6 HDR Plasmid (h) - sc-416977-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BBS6 Double Nickase Plasmid (h) - sc-416977-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BBS6 Double Nickase Plasmid (h2) - sc-416977-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BBS6 CRISPR Activation Plasmid (h) - sc-416977-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

BBS6 CRISPR Activation Plasmid (h2) - sc-416977-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

BBS6 Lentiviral Activation Particles (h) - sc-416977-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BBS6 Lentiviral Activation Particles (h2) - sc-416977-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BBS6 siRNA (h) - sc-60257 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

BBS6 shRNA Plasmid (h) - sc-60257-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

BBS6 shRNA (h) Lentiviral Particles - sc-60257-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU053751 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN14377 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14377 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MKKS siRNA (Human) - CRH5393 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human MKKS (NM_018848.3) - SHH342264 from Creative biogene

Category siRNA
Species Reactivities Human

Human MKKS siRNA - orb265895 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

MKKS shRNA Plasmid (Human) - CHH5393 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

MKKS miRNA 3'UTR clone - MiUTR3H-07181 from Creative biogene

Species Reactivities Human

MKKS miRNA 3'UTR clone - MiUTR3H-07182 from Creative biogene

Species Reactivities Human
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