ZFPM1

Gene Symbol ZFPM1
Entrez Gene 161882
Alt Symbol FOG, FOG1, ZC2HC11A, ZNF408, ZNF89A
Species Human
Gene Type protein-coding
Description zinc finger protein, FOG family member 1
Other Description FOG-1|friend of GATA 1|friend of GATA protein 1|friend of GATA-1|zinc finger protein 89A|zinc finger protein ZFPM1|zinc finger protein, multitype 1
Swissprots Q8IX07
Accessions EAW66806 EAW66807 EAW66808 Q8IX07 AF488691 AAN45858 BE219988 XM_011522912 XP_011521214 XM_011522913 XP_011521215 XM_011522914 XP_011521216 XM_011522915 XP_011521217 XM_011522916 XP_011521218 XM_011522917 XP_011521219 XM_011522918 XP_011521220 NM_153813 NP_722520
Function Transcription regulator that plays an essential role in erythroid and megakaryocytic cell differentiation. Essential cofactor that acts via the formation of a heterodimer with transcription factors of the GATA family GATA1, GATA2 and GATA3. Such heterodimer can both activate or repress transcriptional activity, depending on the cell and promoter context. The heterodimer formed with GATA proteins is essential to activate expression of genes such as NFE2, ITGA2B, alpha- and beta-globin, while it represses expression of KLF1. May be involved in regulation of some genes in gonads. May also be involved in cardiac development, in a non-redundant way with ZFPM2/FOG2 (By similarity). {ECO:0000250}.
Subcellular Location Nucleus {ECO:0000250}.
Tissue Specificity Mainly expressed in hematopoietic tissues. Also expressed in adult cerebellum, stomach, lymph node, liver and pancreas. Expressed in fetal heart, liver and spleen. {ECO:0000269|PubMed:12483298}.

FOG CRISPR/Cas9 KO Plasmid (h) - sc-402620 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FOG HDR Plasmid (h) - sc-402620-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FOG Double Nickase Plasmid (h) - sc-402620-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FOG Double Nickase Plasmid (h2) - sc-402620-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FOG CRISPR Activation Plasmid (h) - sc-402620-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FOG CRISPR Activation Plasmid (h2) - sc-402620-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FOG Lentiviral Activation Particles (h) - sc-402620-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FOG Lentiviral Activation Particles (h2) - sc-402620-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FOG siRNA (h) - sc-35399 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FOG shRNA Plasmid (h) - sc-35399-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FOG shRNA (h) Lentiviral Particles - sc-35399-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ZNF408 RNAi - H00079797-R01 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

ZFPM1 RNAi - H00161882-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU149961 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN23196 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND23196 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR00636 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr00636

ZFPM1 siRNA (Human) - CRJ5938 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ZFPM1 - MBS8236448 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ZFPM1 (NM_153813.2) - SHH452372 from Creative biogene

Category siRNA
Species Reactivities Human

ZFPM1 shRNA Plasmid (Human) - CHJ5938 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ZFPM1 miRNA 3'UTR clone - MiUTR1H-11440 from Creative biogene

Species Reactivities Human
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