MAT2B

Gene Symbol	MAT2B
Entrez Gene	27430
Alt Symbol	MAT-II, MATIIbeta, Nbla02999, SDR23E1, TGR
Species	Human
Gene Type	protein-coding
Description	methionine adenosyltransferase II, beta
Other Description	MAT II beta\|beta regulatory subunit of methionine adenosyltransferase\|dTDP-4-keto-6-deoxy-D-glucose 4-reductase\|methionine adenosyltransferase 2 subunit beta\|putative dTDP-4-keto-6-deoxy-D-glucose 4-reductase\|putative protein product of Nbla02999\|short chain dehydrogenase/reductase family 23E, member 1
Swissprots	B2R5Y6 Q9H3E1 Q27J92 Q567T7 Q9BS89 Q9UJ54 Q9NZL9 Q1WAI7 Q6NYC7 Q3LIE8
Accessions	AAO73603 EAW61517 EAW61518 EAW61519 EAW61520 Q9NZL9 AB073390 BAE45720 AF113225 AAG39296 AF182814 AAF28477 AJ243721 CAB56837 AK096178 AK291919 BAF84608 AK294069 BAH11664 AK312365 BAG35283 AL136664 CAB66599 AM393097 CAL37975 AM393737 CAL38612 AU279489 AW966728 AY358695 AAQ89058 BC005218 AAH05218 BC066645 AAH66645 BC093030 AAH93030 DA146198 DQ395260 ABD59011 DQ413182 DQ413183 ABD85290 HY091756 HY366761 NM_013283 NP_037415 NM_182796 NP_877725
Function	Non-catalytic regulatory subunit of S-adenosylmethionine synthetase 2 (MAT2A), an enzyme that catalyzes the formation of S- adenosylmethionine from methionine and ATP. Regulates the activity of S-adenosylmethionine synthetase 2 by changing its kinetic properties, rendering the enzyme more susceptible to S- adenosylmethionine inhibition. {ECO:0000269\|PubMed:10644686}.
Tissue Specificity	Widely expressed. {ECO:0000269\|PubMed:10644686, ECO:0000269\|PubMed:11337507}.
Top Pathways	Cysteine and methionine metabolism, Biosynthesis of amino acids

MAT IIβ (N-13) - sc-83841 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

MAT IIβ (N-13): sc-83841. Western blot analysis of MAT IIβ expression in human PBL whole cell lysate.

MAT IIβ (Y-18) - sc-83842 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

Anti-MAT2B Antibody (aa80-107, AP) - LS-C262713 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-MAT2B Antibody (aa80-107, APC) - LS-C262716 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-MAT2B Antibody (aa80-107, Biotin) - LS-C262718 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-MAT2B Antibody (aa80-107, Azide-free, HRP) - LS-C262719 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-MAT2B Antibody (aa80-107, FITC) - LS-C262717 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-MAT2B Antibody (aa80-107, PE) - LS-C262729 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-MAT2B Antibody (aa86-116) - LS-C322869 from LifeSpan Bioscience

Prices	$345.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-MAT2B Antibody (aa35-84) - LS-C102696 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Anti-MAT2B Antibody (aa4-16) - LS-C155039 from LifeSpan Bioscience

Prices	$395.00
Sizes	100 µg
Host	Goat
Clonality	Polyclonal

MAT2B antibody (0.3 ug/ml) staining of Human Thymus lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-MAT2B Antibody (aa107-156) - LS-C111720 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

MAT2B antibody LS-C111720 Western blot of Fetal Lung lysate.

Anti-MAT2B Antibody (aa80-107) - LS-C164048 from LifeSpan Bioscience

Prices	$295.00
Sizes	400 µl
Host	Rabbit
Clonality	Polyclonal

Formalin-fixed and paraffin-embedded human breast carcinoma reacted with MAT2B Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Anti-MAT2B Antibody - LS-C332561 from LifeSpan Bioscience

Prices	$305.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Western blot analysis of extracts of various cell lines, using MAT2B antibody.

MAT2B Antibody - NBP1-82797 from Novus Biologicals

Prices	$419.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: MAT2B Antibody [NBP1-82797] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp

MAT2B Antibody - NBP1-56616 from Novus Biologicals

Prices	$329.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: MAT2B Antibody [NBP1-56616] - Human Liver cell lysate, concentration 0.2-1 ug/ml.

MAT2B Antibody - NBP1-82798 from Novus Biologicals

Prices	$419.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: MAT2B Antibody [NBP1-82798] - Analysis in human cell line HepG2.

MAT2B Antibody - NBP2-17230 from Novus Biologicals

Prices	$329.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: MAT2B Antibody [NBP2-17230] - Sample (30 ug of whole cell lysate) A: 293T 10% SDS PAGE gel, diluted at 1:1000.

MAT2B Antibody - H00027430-A01 from Novus Biologicals

Prices	$269.00
Sizes	50 µl
Host	Mouse
Clonality	Polyclonal

MAT2B Antibody - NBP2-26144 from Novus Biologicals

Prices	$299.00
Sizes	100 µg
Host	Goat
Clonality	Polyclonal

Western Blot: MAT2B Antibody [NBP2-26144] - (0.3ug/ml) staining of Human Thymus lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-MAT2B (201-215) antibody produced in rabbit - SAB1101407 from Sigma-Aldrich

Prices	$328.50
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunofluorescence</B><BR/>Anti- MAT2B (201-215) (RB): <B>Cat. No. SAB1101407</B>: Immunofluorescence of HUVEC cells using Anti-MAT2B (201-215) (RB) at a 1:50 dilution, taken at 40× magnification and nuclear staining with Hoescht 33342 (blue). Yale HTCB IF procedure used. Images may have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com

Anti-MAT2B, (N-terminal) antibody produced in rabbit - SAB2103119 from Sigma-Aldrich

Prices	$347.50
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunoblotting</B><BR/>Anti-MAT2B, antibody produced in rabbit: <B>Cat. No. SAB2103119</B>: Immunoblotting analysis of MAT2B in fetal liver tissue lysate with MAT2B anitbody at 1 μg/mL.

Anti-MAT2B antibody produced in rabbit - SAB2103120 from Sigma-Aldrich

Prices	$347.50
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunoblotting</B><BR/>Anti-MAT2B, antibody produced in rabbit: <B>Cat. No. SAB2103120</B>: Immunoblotting analysis of MAT2B in fetal lung tissue lysate with MAT2B anitbody at 1 μg/mL.

Anti-MAT2B (N-terminal) antibody produced in goat - SAB2502086 from Sigma-Aldrich

Prices	$376.00
Sizes	100 µg
Host	Goat
Clonality	Polyclonal

<B>Immunoblotting</B><BR/>Anti-MAT2B (N-terminal) <B>Cat. No. SAB2502086</B>: Immunoblotting (0.3 μg/mL) staining of Human Thymus lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-MAT2B antibody produced in rabbit - HPA037721 from Sigma-Aldrich

Prices	$429.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunohistochemistry</B><BR/>Anti-MAT2B: <B>Cat. No. HPA037721</B>: Immunohistochemical staining of human kidney shows moderate cytoplasmic, membranous and nuclear positivity in tubular cells.

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