Gene Symbol |
Cxcl1
|
Entrez Gene |
14825
|
Alt Symbol |
Fsp, Gro1, KC, Mgsa, N51, Scyb1, gro
|
Species |
Mouse
|
Gene Type |
protein-coding
|
Description |
chemokine (C-X-C motif) ligand 1
|
Other Description |
C-X-C motif chemokine 1|GRO1 oncogene|KC/GR)-alpha|KC/GRO-alpha|alpha-chemokine|growth-regulated alpha protein|platelet-derived growth factor-inducible protein KC|secretory protein N51
|
Swissprots |
P12850
|
Accessions |
AAB03376 AAP32036 EDL05301 P12850 AF352782 AK140312 BC037997 AAH37997 BC132502 AAI32503 BC132504 AAI32505 BQ031102 BY335927 J04596 AAA40131 NM_008176 NP_032202
|
Function |
Has chemotactic activity for neutrophils. Contributes to neutrophil activation during inflammation (By similarity). Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. KC(5-72) shows a highly enhanced hematopoietic activity. {ECO:0000250, ECO:0000269|PubMed:10725737}.
|
Subcellular Location |
Secreted.
|
Top Pathways |
Cytokine-cytokine receptor interaction, NOD-like receptor signaling pathway, Chemokine signaling pathway, Salmonella infection, Legionellosis
|