Gene Symbol | Cxcl1 |
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Entrez Gene | 14825 |
Alt Symbol | Fsp, Gro1, KC, Mgsa, N51, Scyb1, gro |
Species | Mouse |
Gene Type | protein-coding |
Description | chemokine (C-X-C motif) ligand 1 |
Other Description | C-X-C motif chemokine 1|GRO1 oncogene|KC/GR)-alpha|KC/GRO-alpha|alpha-chemokine|growth-regulated alpha protein|platelet-derived growth factor-inducible protein KC|secretory protein N51 |
Swissprots | P12850 |
Accessions | AAB03376 AAP32036 EDL05301 P12850 AF352782 AK140312 BC037997 AAH37997 BC132502 AAI32503 BC132504 AAI32505 BQ031102 BY335927 J04596 AAA40131 NM_008176 NP_032202 |
Function | Has chemotactic activity for neutrophils. Contributes to neutrophil activation during inflammation (By similarity). Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. KC(5-72) shows a highly enhanced hematopoietic activity. {ECO:0000250, ECO:0000269|PubMed:10725737}. |
Subcellular Location | Secreted. |
Top Pathways | Cytokine-cytokine receptor interaction, NOD-like receptor signaling pathway, Chemokine signaling pathway, Salmonella infection, Legionellosis |
GRO1 CRISPR/Cas9 KO Plasmid (m) - sc-420697 from Santa Cruz Biotechnology
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GRO1 HDR Plasmid (m) - sc-420697-HDR from Santa Cruz Biotechnology
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GRO1 Double Nickase Plasmid (m) - sc-420697-NIC from Santa Cruz Biotechnology
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GRO1 Double Nickase Plasmid (m2) - sc-420697-NIC-2 from Santa Cruz Biotechnology
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GRO1 CRISPR Activation Plasmid (m) - sc-420697-ACT from Santa Cruz Biotechnology
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GRO1 CRISPR Activation Plasmid (m2) - sc-420697-ACT-2 from Santa Cruz Biotechnology
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GRO1 Lentiviral Activation Particles (m) - sc-420697-LAC from Santa Cruz Biotechnology
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GRO1 Lentiviral Activation Particles (m2) - sc-420697-LAC-2 from Santa Cruz Biotechnology
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GROå siRNA (m) - sc-72160 from Santa Cruz Biotechnology
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GROå shRNA Plasmid (m) - sc-72160-SH from Santa Cruz Biotechnology
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GROå shRNA (m) Lentiviral Particles - sc-72160-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU081671 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN29435 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND29435 from Sigma-Aldrich
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CXCL1 siRNA (Mouse) - CRM1699 from Cohesion Biosciences
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CXCL1 - MBS8219298 from MyBioSource
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shRNA set against Mouse CXCL1 (NM_008176.3) - SHH272109 from Creative biogene
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GRO1 CRISPR/Cas9 KO Plasmid (m2) - sc-420697-KO-2 from Santa Cruz Biotechnology
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GRO1 HDR Plasmid (m2) - sc-420697-HDR-2 from Santa Cruz Biotechnology
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Mouse CXCL1 siRNA - orb281175 from Biorbyt
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CXCL1 shRNA Plasmid (Mouse) - CHM1699 from Cohesion Biosciences
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