Gene Symbol | ACTN1 |
---|---|
Entrez Gene | 87 |
Alt Symbol | BDPLT15 |
Species | Human |
Gene Type | protein-coding |
Description | actinin, alpha 1 |
Other Description | F-actin cross-linking protein|actinin 1 smooth muscle|alpha-actinin cytoskeletal isoform|alpha-actinin-1|non-muscle alpha-actinin-1 |
Swissprots | Q1HE25 P12814 B4DHH3 B7TY16 B3V8S3 Q9BTN1 |
Accessions | EAW80971 EAW80972 EAW80973 EAW80974 EAW80975 EAW80976 P12814 AJ844628 CAH59747 AK098203 BAG53591 AK124378 AK225782 AK294317 BAG57591 AK295099 BAG58135 AK298496 BAH12801 AK299362 BAG61357 BC003576 AAH03576 BC004984 BC011987 BC015766 AAH15766 BC127124 AAI27125 BI494856 BT007207 AAP35871 BX248020 CAD62344 BX641076 DC321454 DC372566 DQ496098 ABF50047 DQ890778 ABM81704 DQ895768 ABM86694 EU716325 ACE62922 FJ410030 ACJ24535 M95178 AAA51582 X15804 CAA33803 X55187 CAA38970 XM_011537265 XP_011535567 XM_011537266 XP_011535568 XM_011537267 XP_011535569 XM_011537268 XP_011535570 XM_011537269 XP_011535571 XM_011537270 XP_011535572 XM_011537271 XP_011535573 NM_001102 NP_001093 NM_001130004 NP_001123476 NM_001130005 NP_001123477 |
Function | F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. |
Subcellular Location | Cytoplasm, cytoskeleton {ECO:0000269|PubMed:24069336, ECO:0000269|PubMed:7750553}. Cytoplasm, myofibril, sarcomere, Z line {ECO:0000269|PubMed:7750553}. Cell membrane {ECO:0000250}. Cell junction {ECO:0000250}. Cell projection, ruffle {ECO:0000250}. Note=Colocalizes with MYOZ2 and PPP3CA at the Z-line of heart and skeletal muscle. Colocalizes with PSD in membrane ruffles and central reticular structures (By similarity). {ECO:0000250}. |
Top Pathways | Systemic lupus erythematosus, Adherens junction, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Leukocyte transendothelial migration, Amoebiasis |
α-Actinin (D6F6) XP ® Rabbit mAb (HRP Conjugate) - 12413 from Cell Signaling Technology
|
||||||||||
α-Actinin (D6F6) XP ® Rabbit mAb - 6487 from Cell Signaling Technology
|
||||||||||
α-Actinin Antibody - 3134 from Cell Signaling Technology
|
||||||||||
α-actinin (H-2) - sc-17829 from Santa Cruz Biotechnology
|
||||||||||
α-actinin-1 (23) - sc-135819 from Santa Cruz Biotechnology
|
||||||||||
Anti-alpha Actinin antibody - ab199290 from Abcam
|
||||||||||
Anti-alpha Actinin antibody [0.T.02] - ab18061 from Abcam
|
||||||||||
Anti-alpha Actinin antibody [7A4] - ab90421 from Abcam
|
||||||||||
Anti-alpha Actinin antibody [AT6.172] - ab78505 from Abcam
|
||||||||||
Anti-alpha Actinin antibody [EP2527Y] - ab68194 from Abcam
|
||||||||||
Anti-alpha Actinin antibody [EP2528Y] - ab81265 from Abcam
|
||||||||||
Anti-alpha Actinin antibody [SA-20] - ab82247 from Abcam
|
||||||||||
Anti-ACTN1 Antibody - LS-C34853 from LifeSpan Bioscience
|
||||||||||
Anti-ACTN1 Antibody (N-Terminus) - LS-C34858 from LifeSpan Bioscience
|
||||||||||
Anti-ACTN1 Antibody - LS-C121110 from LifeSpan Bioscience
|
||||||||||
Anti-ACTN1 Antibody (clone CB11) - LS-C122583 from LifeSpan Bioscience
|
||||||||||
Anti-ACTN1 Antibody (C-Terminus) - LS-C126580 from LifeSpan Bioscience
|
||||||||||
Anti-ACTN1 Antibody - LS-C126581 from LifeSpan Bioscience
|
||||||||||
Anti-ACTN1 Antibody (N-Terminus, AP) - LS-C274856 from LifeSpan Bioscience
|
||||||||||
Anti-ACTN1 Antibody (C-Terminus, clone EP2528Y) - LS-C137690 from LifeSpan Bioscience
|
||||||||||
Anti-ACTN1 Antibody (N-Terminus) - LS-C102772 from LifeSpan Bioscience
|
||||||||||
Anti-ACTN1 Antibody (N-Terminus, clone EP2527Y) - LS-C105275 from LifeSpan Bioscience
|
||||||||||
Anti-ACTN1 Antibody - LS-C183484 from LifeSpan Bioscience
|
||||||||||
Anti-ACTN1 Antibody (N-Terminus, Biotin) - LS-C274857 from LifeSpan Bioscience
|
||||||||||
Anti-ACTN1 Antibody (N-Terminus, Azide-free, HRP) - LS-C274859 from LifeSpan Bioscience
|