| Gene Symbol | ZFYVE28 |
|---|---|
| Entrez Gene | 57732 |
| Alt Symbol | LST2, LYST2 |
| Species | Human |
| Gene Type | protein-coding |
| Description | zinc finger, FYVE domain containing 28 |
| Other Description | hLst2|lateral signaling target protein 2 homolog|zinc finger FYVE domain-containing protein 28 |
| Swissprots | E9PG77 E9PB64 B7Z2G9 B7ZB19 B7Z1Q7 B2RP83 B7Z2M2 Q9HCC9 B3KX50 E9PB54 Q7Z6J3 |
| Accessions | EAW82528 EAW82529 Q9HCC9 AB046863 BAB13469 AK126692 BAG54362 AK293775 BAH11593 AK294710 BAH11855 AK294874 BAH11908 AK316484 BAH14855 BC032605 BC035793 BC041866 AAH41866 BC053664 AAH53664 BC137309 AAI37310 BC137310 AAI37311 BM128958 XM_006713900 XP_006713963 XM_006713901 XP_006713964 XM_006713902 XP_006713965 XM_006713903 XP_006713966 XM_006713904 XP_006713967 XM_011513539 XP_011511841 XM_011513540 XP_011511842 XM_011513541 XP_011511843 NM_001172656 NP_001166127 NM_001172657 NP_001166128 NM_001172658 NP_001166129 NM_001172659 NP_001166130 NM_001172660 NP_001166131 NM_020972 NP_066023 |
| Function | Negative regulator of epidermal growth factor receptor (EGFR) signaling. Acts by promoting EGFR degradation in endosomes when not monoubiquitinated. {ECO:0000269|PubMed:19460345}. |
| Subcellular Location | Cytoplasm, cytosol {ECO:0000269|PubMed:19460345}. Early endosome membrane {ECO:0000269|PubMed:19460345}. Note=Localizes to early endosome membrane in absence of Lys-87 monoubiquitination. Localizes to cytosol when monoubiquitinated. |
Human ZFYVE28 cDNA clone(NM_001172656.1) - CDFH021623 from Creative Biomart
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Human ZFYVE28 cDNA clone(NM_001172657.1) - CDFH021624 from Creative Biomart
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Human ZFYVE28 cDNA clone(NM_001172658.1) - CDFH021625 from Creative Biomart
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Human ZFYVE28 cDNA clone(NM_001172659.1) - CDFH021626 from Creative Biomart
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Human ZFYVE28 cDNA clone(NM_001172660.1) - CDFH021627 from Creative Biomart
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Human ZFYVE28 ORF Clone(NM_001172656.1) - CDCL182012 from Creative Biomart
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Human ZFYVE28 ORF Clone(NM_001172656.1) - CDCR356451 from Creative Biomart
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Human ZFYVE28 ORF Clone(NM_001172658.1) - CDCR356452 from Creative Biomart
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Human ZFYVE28 ORF Clone(NM_001172658.1) - CDCR356453 from Creative Biomart
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Human ZFYVE28 ORF Clone(NM_001172659.1) - CDCR356454 from Creative Biomart
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Human ZFYVE28 ORF Clone(NM_001172660.1) - CDCR356455 from Creative Biomart
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Human ZFYVE28 ORF Clone(NM_001172660.1) - CDCR356456 from Creative Biomart
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Human ZFYVE28 ORF Clone(NM_001172659.1) - CDCR356458 from Creative Biomart
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Human ZFYVE28 ORF Clone(NM_001172656.1) - CDCR356608 from Creative Biomart
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Human ZFYVE28 ORF Clone(NM_001172657.1) - CDCR356609 from Creative Biomart
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Human ZFYVE28 ORF Clone(NM_001172657.1) - CDCR356610 from Creative Biomart
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human ZFYVE28 ORF clone - CDCH104314 from Creative Biomart
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human ZFYVE28 ORF clone - CDCH104315 from Creative Biomart
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human ZFYVE28 ORF clone - CDCH104316 from Creative Biomart
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human ZFYVE28 ORF clone - CDCH104317 from Creative Biomart
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human ZFYVE28 ORF clone - CDCH104318 from Creative Biomart
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human ZFYVE28 ORF clone - CDCH104319 from Creative Biomart
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human ZFYVE28 ORF clone - CDCH104320 from Creative Biomart
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human ZFYVE28 ORF clone - CDCH104321 from Creative Biomart
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human ZFYVE28 ORF clone - CDCH104322 from Creative Biomart
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