PCDH15

Gene Symbol PCDH15
Entrez Gene 65217
Alt Symbol CDHR15, DFNB23, USH1F
Species Human
Gene Type protein-coding
Description protocadherin-related 15
Other Description cadherin-related family member 15|protocadherin-15
Swissprots C6ZEF6 Q5VY38 Q96QU1 Q6TRH8 Q8NDB9 C6ZEF7 Q5VY39 A6NL19 Q96QT8 C6ZEF5
Accessions EAW54151 EAW54152 Q96QU1 AK126923 BAG54399 AL834134 CAD38850 AW005431 AY029205 AAK31581 AY029237 AAK31804 AY388963 AAR26468 BC156450 AAI56451 EU718480 ACF76476 EU718481 ACF76477 EU718482 ACF76478 NM_001142763 NP_001136235 NM_001142764 NP_001136236 NM_001142765 NP_001136237 NM_001142766 NP_001136238 NM_001142767 NP_001136239 NM_001142768 NP_001136240 NM_001142769 NP_001136241 NM_001142770 NP_001136242 NM_001142771 NP_001136243 NM_001142772 NP_001136244 NM_001142773 NP_001136245 NM_033056 NP_149045
Function Calcium-dependent cell-adhesion protein. Essential for maintenance of normal retinal and cochlear function.
Subcellular Location Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Note=Efficient localization to the plasma membrane requires the presence of LHFPL5. {ECO:0000250}.
Tissue Specificity Expressed in brain, lung, kidney, spleen and testis. Found also in the inner and outer synaptic layers, and the nerve fiber layer in adult and fetal retinas. Found in the supporting cells, outer sulcus cells and spiral ganglion of fetal cochlea. Expressed in cytotoxic tumor-derived T- and NK-cell lines as well as biopsies of nasal NK/T-cell lymphomas. Not detected in normal or in vitro activated peripheral blood cells, CD4 or CD8 lymphocytes or NK cells. Isoform 3 is expressed in brain, heart, cerebellum and kidney. CD1 isoforms, such as isoform 1, have a limited pattern of expression and is detected in testis, retina and cochlea. CD2 isoforms, such as isoforms 4 and 5, are expressed in heart, kidney, thymus, spleen, testis, retina and cochlea. CD3 isoforms, such as isoform 6, are widely expressed. {ECO:0000269|PubMed:11487575, ECO:0000269|PubMed:16369489, ECO:0000269|PubMed:18719945}.

PCDH15 Blocking Peptide - 33R-3853 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

Recombinant Protocadherin 15 (PCDH15) - RPE095Hu01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Human

Recombinant Protocadherin 15 (PCDH15) - RPE095Mu01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Mouse

Recombinant Protocadherin 15 (PCDH15) - RPE095Mu02 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Mouse

Recombinant Protocadherin 15 (PCDH15) - RPE095Hu01 from Cloud-clone

Category Protein
Source E.coli
Species Human

Recombinant Human Protocadherin-15(PCDH15) ,partial - CSB-YP853490HU CSB-EP853490HU CSB-BP853490HU CSB-MP853490HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

PCDH15 Peptide, Human - M34GP11373H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

Protocadherin 15, Recombinant Protein - MBS2033494 from MyBioSource

Category Protein
Prices $175.00, $370.00, $575.00
Sizes 10 µg, 50 µg, 100 µg
Source Prokaryotic expression
Species Mouse

Protocadherin-15 (PCDH15), partial, Recombinant Protein - MBS1481301 from MyBioSource

Category Protein
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human
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