Chst2

Gene Symbol Chst2
Entrez Gene 54371
Alt Symbol AI428561, AW121776, C130041E03Rik, Chts2, GST-2, GlcNAc6ST, Gn6st
Species Mouse
Gene Type protein-coding
Description carbohydrate sulfotransferase 2
Other Description N-acetylglucosamine 6-O-sulfotransferase 1|N-acetylglucosamine-6-O-sulfotransferase|galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 2|glcNAc6ST-1|gn6st-1
Swissprots Q794G9 O88276 Q80WV3 E9QNG2
Accessions BAD16775 CAL85379 EDL20935 Q80WV3 AB011451 BAA32137 AB011452 BAA32138 AK034634 AK048226 AK131820 BAE20819 AW121776 BC051963 AAH51963 BM947059 BM950407 BU701895 CJ172365 NM_018763 NP_061233
Function Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues within keratan-like structures on N-linked glycans and within mucin-associated glycans that can ultimately serve as SELL ligands. SELL ligands are present in high endothelial cells (HEVs) and play a central role in lymphocyte homing at sites of inflammation. Participates in biosynthesis of the SELL ligand sialyl 6-sulfo Lewis X and in lymphocyte homing to Peyer patches. Has no activity toward O-linked sugars. Its substrate specificity may be influenced by its subcellular location. Sulfates GlcNAc residues at terminal, non-reducing ends of oligosaccharide chains. {ECO:0000269|PubMed:15175329, ECO:0000269|PubMed:9712885}.
Subcellular Location Golgi apparatus, trans-Golgi network membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Tissue Specificity In brain, it is expressed in pyramidal cells in the CA3 subregion of the hippocampus, cerebellar nucleus and Purkinje cells. {ECO:0000269|PubMed:9712885, ECO:0000269|PubMed:9722682}.
Top Pathways Glycosaminoglycan biosynthesis - keratan sulfate

Recombinant Mouse Carbohydrate sulfotransferase 2(Chst2) - CSB-YP773926MO CSB-EP773926MO CSB-BP773926MO CSB-MP773926MO from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Mouse

Carbohydrate sulfotransferase 2 (Chst2), Recombinant Protein - MBS1424274 from MyBioSource

Category Protein
Prices $780.00, $780.00, $1,005.00, $1,005.00, $1,085.00, $1,085.00, $1,540.00, $1,540.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Mouse

Recombinant Mouse CHST2 Protein - CHST2-3451M from Creative Biomart

Category Protein
Source Mammalian Cells
Species Mouse
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