GATA4

Gene Symbol GATA4
Entrez Gene 2626
Alt Symbol ASD2, TACHD, TOF, VSD1
Species Human
Gene Type protein-coding
Description GATA binding protein 4
Other Description GATA-binding factor 4|transcription factor GATA-4
Swissprots Q5IFM8 P43694 Q3MJ45 B7ZKZ4 B7ZKX0
Accessions AAA70335 ABY49125 ABY84859 ABY84860 ABY84861 ABY84862 ABY84863 ABY84864 ABY84865 ACD13586 ACD13587 EAW65620 EAW65621 P43694 AF180736 AF318320 AAL55827 AI192760 AK097060 BAG53416 AY740706 AAW51922 BC033672 BC068079 BC101580 AAI01581 BC105108 AAI05109 BC143434 AAI43435 BC143479 AAI43480 BM560562 BM768332 BQ439274 D78260 BAA11334 DA900813 DR003768 FJ169610 ACI04537 HY015197 HY023604 L34357 AAA58496 XM_005272384 XP_005272441 XM_005272385 XP_005272442 XM_005272386 XP_005272443 XM_006716248 XP_006716311 XM_006716249 XP_006716312 XM_011543817 XP_011542119 XM_011543818 XP_011542120 NM_001308093 NP_001295022 NM_001308094 NP_001295023 NM_002052 NP_002043
Function Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development. Involved in bone morphogenetic protein (BMP)-mediated induction of cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions. Acts as a transcriptional activator of ANF in cooperation with NKX2-5. Promotes cardiac myocyte enlargement. Required during testicular development. {ECO:0000269|PubMed:20081228, ECO:0000269|PubMed:21220346, ECO:0000269|PubMed:24000169}.
Subcellular Location Nucleus {ECO:0000269|PubMed:21220346, ECO:0000269|PubMed:24000169}.
Top Pathways cGMP-PKG signaling pathway

GATA-4 CRISPR/Cas9 KO Plasmid (h) - sc-400122 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GATA-4 HDR Plasmid (h) - sc-400122-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GATA-4 Double Nickase Plasmid (h) - sc-400122-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GATA-4 Double Nickase Plasmid (h2) - sc-400122-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GATA-4 CRISPR Activation Plasmid (h) - sc-400122-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GATA-4 CRISPR Activation Plasmid (h2) - sc-400122-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GATA-4 Lentiviral Activation Particles (h) - sc-400122-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GATA-4 Lentiviral Activation Particles (h2) - sc-400122-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GATA-4 siRNA (h) - sc-35455 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GATA-4 shRNA Plasmid (h) - sc-35455-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GATA-4 shRNA (h) Lentiviral Particles - sc-35455-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU085401 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN9149 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9149 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

GATA4 siRNA (Human) - CRH1742 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GATA-4 RNAi - H00002626-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

GATA4 - MBS8224882 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human GATA4 (NM_002052.3) - SHH299562 from Creative biogene

Category siRNA
Species Reactivities Human

GATA-4 CRISPR/Cas9 KO Plasmid (h2) - sc-400122-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GATA-4 HDR Plasmid (h2) - sc-400122-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Human GATA4 siRNA - orb262244 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GATA4 shRNA Plasmid (Human) - CHH1742 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

GATA4 miRNA 3'UTR clone - MiUTR3H-03486 from Creative biogene

Species Reactivities Human
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