| Gene Symbol |
FGF8
|
| Entrez Gene |
2253
|
| Alt Symbol |
AIGF, FGF-8, HBGF-8, HH6, KAL6
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
fibroblast growth factor 8 (androgen-induced)
|
| Other Description |
androgen-induced growth factor|fibroblast growth factor 8|heparin-binding growth factor 8
|
| Swissprots |
A1A514 P55075 Q15766 Q14915
|
| Accessions |
AAB17894 AAB34255 AAC50782 AAC50783 AAC50784 AAC50785 AAM55238 BAA22527 CAI53480 EAW49746 EAW49747 EAW49748 EAW49749 EAW49750 P55075 AB014615 BAA28605 BC069106 AAH69106 BC128235 AAI28236 BC128236 AAI28237 CN369230 U36223 AAB17893 U46211 AAB40953 U46212 AAB40954 U46213 AAB40955 U56978 AAB03787 XM_011539509 XP_011537811 NM_001206389 NP_001193318 NM_006119 NP_006110 NM_033163 NP_149353 NM_033164 NP_149354 NM_033165 NP_149355
|
| Function |
Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. Required for normal brain, eye, ear and limb development during embryogenesis. Required for normal development of the gonadotropin-releasing hormone (GnRH) neuronal system (PubMed:16384934, PubMed:16597617, PubMed:8663044). Plays a role in neurite outgrowth in hippocampal cells (PubMed:21576111). {ECO:0000269|PubMed:16384934, ECO:0000269|PubMed:16597617, ECO:0000269|PubMed:21576111, ECO:0000269|PubMed:8663044}.
|
| Subcellular Location |
Secreted.
|
| Top Pathways |
Melanoma, MAPK signaling pathway, PI3K-Akt signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton
|