Gene Symbol | FGF8 |
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Entrez Gene | 2253 |
Alt Symbol | AIGF, FGF-8, HBGF-8, HH6, KAL6 |
Species | Human |
Gene Type | protein-coding |
Description | fibroblast growth factor 8 (androgen-induced) |
Other Description | androgen-induced growth factor|fibroblast growth factor 8|heparin-binding growth factor 8 |
Swissprots | A1A514 P55075 Q15766 Q14915 |
Accessions | AAB17894 AAB34255 AAC50782 AAC50783 AAC50784 AAC50785 AAM55238 BAA22527 CAI53480 EAW49746 EAW49747 EAW49748 EAW49749 EAW49750 P55075 AB014615 BAA28605 BC069106 AAH69106 BC128235 AAI28236 BC128236 AAI28237 CN369230 U36223 AAB17893 U46211 AAB40953 U46212 AAB40954 U46213 AAB40955 U56978 AAB03787 XM_011539509 XP_011537811 NM_001206389 NP_001193318 NM_006119 NP_006110 NM_033163 NP_149353 NM_033164 NP_149354 NM_033165 NP_149355 |
Function | Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. Required for normal brain, eye, ear and limb development during embryogenesis. Required for normal development of the gonadotropin-releasing hormone (GnRH) neuronal system (PubMed:16384934, PubMed:16597617, PubMed:8663044). Plays a role in neurite outgrowth in hippocampal cells (PubMed:21576111). {ECO:0000269|PubMed:16384934, ECO:0000269|PubMed:16597617, ECO:0000269|PubMed:21576111, ECO:0000269|PubMed:8663044}. |
Subcellular Location | Secreted. |
Top Pathways | Melanoma, MAPK signaling pathway, PI3K-Akt signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton |
Active human FGF8 full length protein - ab192120 from Abcam
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Human FGF8 protein fragment - ab50128 from Abcam
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FGF8 Antibody Blocking Peptide - LS-E6755 from LifeSpan Bioscience
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FGF8 Antibody Blocking Peptide - LS-E23057 from LifeSpan Bioscience
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FGF8 Antibody Blocking Peptide - LS-E23058 from LifeSpan Bioscience
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FGF-8 Recombinant Protein - P3967 from Novus Biologicals
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Recombinant Human FGF-8 Protein - NBP1-99966 from Novus Biologicals
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FGF-8 Protein - NBP1-99826 from Novus Biologicals
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FGF8 recombinant protein - GTX65087 from GeneTex
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FGF8 Recombinant Protein (Active) - GTX48450-PRO from GeneTex
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Recombinant Human/Mouse FGF-8b - 423-F8-025 from R&D Systems
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Recombinant Human/Mouse FGF-8b, CF - 423-F8-025/CF from R&D Systems
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Recombinant Human FGF-8a, CF - 4745-F8-050 from R&D Systems
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Recombinant Human FGF-8f - 5027-FF-025 from R&D Systems
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Recombinant Human FGF-8f, CF - 5027-FF-025/CF from R&D Systems
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Recombinant Human FGF-8e, CF - 4746-F8-050 from R&D Systems
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Human FGF 8 Protein (OPSA11010) - OPSA11010 from Aviva Systems Biology
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Murine FGF-8 protein - orb107713 from Biorbyt
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Human FGF 8 protein - orb168356 from Biorbyt
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Mouse FGF 8 protein - orb168357 from Biorbyt
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FGF8 protein - 30R-2440 from Fitzgerald
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FGF8 protein - 30R-AF010 from Fitzgerald
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Pleiotrophin protein - 30R-AP009 from Fitzgerald
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FGF8 (FGF-8B) - PA144 from Acris Antibodies
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FGF8 (FGF-8B) - PA144X from Acris Antibodies
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