Gene Symbol | FGF8 |
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Entrez Gene | 2253 |
Alt Symbol | AIGF, FGF-8, HBGF-8, HH6, KAL6 |
Species | Human |
Gene Type | protein-coding |
Description | fibroblast growth factor 8 (androgen-induced) |
Other Description | androgen-induced growth factor|fibroblast growth factor 8|heparin-binding growth factor 8 |
Swissprots | A1A514 P55075 Q15766 Q14915 |
Accessions | AAB17894 AAB34255 AAC50782 AAC50783 AAC50784 AAC50785 AAM55238 BAA22527 CAI53480 EAW49746 EAW49747 EAW49748 EAW49749 EAW49750 P55075 AB014615 BAA28605 BC069106 AAH69106 BC128235 AAI28236 BC128236 AAI28237 CN369230 U36223 AAB17893 U46211 AAB40953 U46212 AAB40954 U46213 AAB40955 U56978 AAB03787 XM_011539509 XP_011537811 NM_001206389 NP_001193318 NM_006119 NP_006110 NM_033163 NP_149353 NM_033164 NP_149354 NM_033165 NP_149355 |
Function | Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. Required for normal brain, eye, ear and limb development during embryogenesis. Required for normal development of the gonadotropin-releasing hormone (GnRH) neuronal system (PubMed:16384934, PubMed:16597617, PubMed:8663044). Plays a role in neurite outgrowth in hippocampal cells (PubMed:21576111). {ECO:0000269|PubMed:16384934, ECO:0000269|PubMed:16597617, ECO:0000269|PubMed:21576111, ECO:0000269|PubMed:8663044}. |
Subcellular Location | Secreted. |
Top Pathways | Melanoma, MAPK signaling pathway, PI3K-Akt signaling pathway, Rap1 signaling pathway, Regulation of actin cytoskeleton |
FGF-8 (H-181) - sc-7916 from Santa Cruz Biotechnology
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FGF-8 (N-19) - sc-6958 from Santa Cruz Biotechnology
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FGF-8 (P-18) - sc-27144 from Santa Cruz Biotechnology
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Anti-FGF8 antibody - ab81384 from Abcam
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Anti-FGF8 antibody - ab203030 from Abcam
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Anti-FGF8 antibody - ab54756 from Abcam
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Anti-FGF8 antibody [MM0291-8D24] - ab89550 from Abcam
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Anti-FGF8 antibody - N-terminal - ab202327 from Abcam
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Anti-FGF8 Antibody (aa32-66) - LS-C344463 from LifeSpan Bioscience
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Anti-FGF8 Antibody (clone 2A10) - LS-C197214 from LifeSpan Bioscience
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Anti-FGF8 Antibody (C-Terminus) - LS-C121817 from LifeSpan Bioscience
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Anti-FGF8 Antibody - LS-C147088 from LifeSpan Bioscience
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Anti-FGF8 Antibody (C-Terminus, Sepharose) - LS-C171972 from LifeSpan Bioscience
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Anti-FGF8 Antibody (C-Terminus, Magnetic beads) - LS-C171971 from LifeSpan Bioscience
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Anti-FGF8 Antibody (C-Terminus) - LS-C146310 from LifeSpan Bioscience
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Anti-FGF8 Antibody (aa2-233) - LS-C311483 from LifeSpan Bioscience
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Anti-FGF8 Antibody (C-Terminus) - LS-C171970 from LifeSpan Bioscience
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Anti-FGF8 Antibody (aa104-153) - LS-C151511 from LifeSpan Bioscience
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FGF-8 Antibody (47109) - MAB323 from Novus Biologicals
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FGF-8 Antibody - AF-423-NA from Novus Biologicals
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FGF-8 Antibody - NBP1-98443 from Novus Biologicals
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FGF-8 Antibody - NBP1-41493 from Novus Biologicals
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FGF-8 Antibody (2A10) - H00002253-M01 from Novus Biologicals
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FGF-8 Antibody (MM0291-8D24) - NBP2-12305 from Novus Biologicals
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FGF-8 Antibody (3H2) - H00002253-M06 from Novus Biologicals
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