| Gene Symbol |
COA3
|
| Entrez Gene |
28958
|
| Alt Symbol |
CCDC56, HSPC009, MITRAC12
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
cytochrome c oxidase assembly factor 3
|
| Other Description |
coiled-coil domain-containing protein 56|cytochrome C oxidase assembly factor 3 homolog, mitochondrial|cytochrome c oxidase assembly factor 3 homolog, mitochondrial|cytochrome c oxidase assembly protein 3 homolog, mitochondrial|mitochondrial translation regulation assembly intermediate of cytochrome c oxidase protein of 12 kDa
|
| Swissprots |
Q9Y2R0 A8K498
|
| Accessions |
EAW60884 EAW60885 Q9Y2R0 AF070665 AAD20971 AK225611 AK290863 BAF83552 AK295023 BAH11952 AL524532 AU122748 BC002698 AAH02698 DQ893448 ABM84374 EU176748 ABW03549 L38939 NM_001040431 NP_001035521
|
| Function |
Component of some MITRAC complex, a cytochrome c oxidase (COX) assembly intermediate complex that regulates COX assembly. MITRAC complexes regulate both translation of mitochondrial encoded components and assembly of nuclear-encoded components imported in mitochondrion. Required for efficient translation of MT-CO1 and mitochondrial respiratory chain complex IV assembly. {ECO:0000269|PubMed:23260140}.
|
| Subcellular Location |
Mitochondrion inner membrane {ECO:0000269|PubMed:23260140}; Single-pass membrane protein {ECO:0000269|PubMed:23260140}.
|
![Western Blot: CCDC56 Overexpression Lysate (Adult Normal) [NBL1-08806] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for CCDC56.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/6351_CCDC56%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-08806-img0002.jpg)