Gene Symbol | COA3 |
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Entrez Gene | 28958 |
Alt Symbol | CCDC56, HSPC009, MITRAC12 |
Species | Human |
Gene Type | protein-coding |
Description | cytochrome c oxidase assembly factor 3 |
Other Description | coiled-coil domain-containing protein 56|cytochrome C oxidase assembly factor 3 homolog, mitochondrial|cytochrome c oxidase assembly factor 3 homolog, mitochondrial|cytochrome c oxidase assembly protein 3 homolog, mitochondrial|mitochondrial translation regulation assembly intermediate of cytochrome c oxidase protein of 12 kDa |
Swissprots | Q9Y2R0 A8K498 |
Accessions | EAW60884 EAW60885 Q9Y2R0 AF070665 AAD20971 AK225611 AK290863 BAF83552 AK295023 BAH11952 AL524532 AU122748 BC002698 AAH02698 DQ893448 ABM84374 EU176748 ABW03549 L38939 NM_001040431 NP_001035521 |
Function | Component of some MITRAC complex, a cytochrome c oxidase (COX) assembly intermediate complex that regulates COX assembly. MITRAC complexes regulate both translation of mitochondrial encoded components and assembly of nuclear-encoded components imported in mitochondrion. Required for efficient translation of MT-CO1 and mitochondrial respiratory chain complex IV assembly. {ECO:0000269|PubMed:23260140}. |
Subcellular Location | Mitochondrion inner membrane {ECO:0000269|PubMed:23260140}; Single-pass membrane protein {ECO:0000269|PubMed:23260140}. |
CCDC56 CRISPR/Cas9 KO Plasmid (h) - sc-409260 from Santa Cruz Biotechnology
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CCDC56 HDR Plasmid (h) - sc-409260-HDR from Santa Cruz Biotechnology
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CCDC56 Double Nickase Plasmid (h) - sc-409260-NIC from Santa Cruz Biotechnology
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CCDC56 Double Nickase Plasmid (h2) - sc-409260-NIC-2 from Santa Cruz Biotechnology
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CCDC56 CRISPR Activation Plasmid (h) - sc-409260-ACT from Santa Cruz Biotechnology
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CCDC56 CRISPR Activation Plasmid (h2) - sc-409260-ACT-2 from Santa Cruz Biotechnology
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CCDC56 Lentiviral Activation Particles (h) - sc-409260-LAC from Santa Cruz Biotechnology
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CCDC56 Lentiviral Activation Particles (h2) - sc-409260-LAC-2 from Santa Cruz Biotechnology
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CCDC56 siRNA (h) - sc-93975 from Santa Cruz Biotechnology
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CCDC56 shRNA Plasmid (h) - sc-93975-SH from Santa Cruz Biotechnology
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CCDC56 shRNA (h) Lentiviral Particles - sc-93975-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU126321 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5539 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5539 from Sigma-Aldrich
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COA3 siRNA (Human) - CRH9127 from Cohesion Biosciences
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COA3 - MBS827674 from MyBioSource
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shRNA set against Human CCDC56 (NM_001040431.1) - SHH256813 from Creative biogene
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shRNA set against Human CCDC56(NM_001040431.1) - SHG148883 from Creative biogene
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Human COA3 siRNA - orb269629 from Biorbyt
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COA3 shRNA Plasmid (Human) - CHH9127 from Cohesion Biosciences
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COA3 miRNA 3'UTR clone - MiUTR1H-01757 from Creative biogene
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