Gene Symbol | COA3 |
---|---|
Entrez Gene | 28958 |
Alt Symbol | CCDC56, HSPC009, MITRAC12 |
Species | Human |
Gene Type | protein-coding |
Description | cytochrome c oxidase assembly factor 3 |
Other Description | coiled-coil domain-containing protein 56|cytochrome C oxidase assembly factor 3 homolog, mitochondrial|cytochrome c oxidase assembly factor 3 homolog, mitochondrial|cytochrome c oxidase assembly protein 3 homolog, mitochondrial|mitochondrial translation regulation assembly intermediate of cytochrome c oxidase protein of 12 kDa |
Swissprots | Q9Y2R0 A8K498 |
Accessions | EAW60884 EAW60885 Q9Y2R0 AF070665 AAD20971 AK225611 AK290863 BAF83552 AK295023 BAH11952 AL524532 AU122748 BC002698 AAH02698 DQ893448 ABM84374 EU176748 ABW03549 L38939 NM_001040431 NP_001035521 |
Function | Component of some MITRAC complex, a cytochrome c oxidase (COX) assembly intermediate complex that regulates COX assembly. MITRAC complexes regulate both translation of mitochondrial encoded components and assembly of nuclear-encoded components imported in mitochondrion. Required for efficient translation of MT-CO1 and mitochondrial respiratory chain complex IV assembly. {ECO:0000269|PubMed:23260140}. |
Subcellular Location | Mitochondrion inner membrane {ECO:0000269|PubMed:23260140}; Single-pass membrane protein {ECO:0000269|PubMed:23260140}. |