Gene Symbol | HHIP |
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Entrez Gene | 64399 |
Alt Symbol | HIP |
Species | Human |
Gene Type | protein-coding |
Description | hedgehog interacting protein |
Other Description | hedgehog-interacting protein |
Swissprots | Q9H7E7 Q6PK09 Q9BXK3 Q8NCI7 Q9H1J4 Q96QV1 |
Accessions | AAK18182 CAK96038 CBI67672 EAX05054 Q96QV1 AK024645 BAB14945 AK074711 BAC11154 AK098525 AK291849 BAF84538 AY009317 AAG35411 AY009951 AAG34731 AY358747 AAQ89107 BC009298 AAH09298 BC015636 BC025311 AAH25311 BI602235 DQ893618 ABM84544 XM_005263178 XP_005263235 XM_006714288 XP_006714351 NM_022475 NP_071920 |
Function | Modulates hedgehog signaling in several cell types including brain and lung through direct interaction with members of the hedgehog family. {ECO:0000269|PubMed:11472839, ECO:0000269|PubMed:19561609}. |
Subcellular Location | Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Secreted {ECO:0000250}. Note=The last 22 C-terminal amino acids may participate in cell membrane attachment. |
Tissue Specificity | Widely expressed in fetal and adult tissues. Highest expression in adult heart, liver and pancreas, and in fetal kidney. {ECO:0000269|PubMed:11435703, ECO:0000269|Ref.1}. |
Top Pathways | Hedgehog signaling pathway, Basal cell carcinoma, cAMP signaling pathway |
Human Hhip peptide - ab39947 from Abcam
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Human Hhip protein fragment - ab153485 from Abcam
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HHIP / HIP Antibody Blocking Peptide - LS-E5527 from LifeSpan Bioscience
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Recombinant Human Hip Protein - H00064399-Q01 from Novus Biologicals
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HHIP-Antibody-N-term-Blocking-Peptide - BP18055a from Abgent, a WuXi AppTec company
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Hedgehog-interacting protein / HHIP - H00064399-Q01-10 from Acris Antibodies
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Hedgehog-interacting protein / HHIP - H00064399-Q01-25 from Acris Antibodies
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HHIP fusion protein - ag2241 from Proteintech Group
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Recombinant Hedgehog Interacting Protein (HHIP) - RPC524Hu01 from Uscn Life Science Inc.
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Recombinant Hedgehog Interacting Protein (HHIP) - RPC524Mu01 from Uscn Life Science Inc.
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Recombinant Hedgehog Interacting Protein (HHIP) - RPC524Mu02 from Uscn Life Science Inc.
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Recombinant Human Hedgehog-interacting protein(HHIP) - CSB-YP850419HU CSB-EP850419HU CSB-BP850419HU CSB-MP850419HU from Cusabio
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HHIP Peptide, Human - M34GP06974H from Creative Peptides
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Recombinant Human Hip Protein, CF - 9280-HP from R&D Systems
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Hedgehog-interacting protein (HHIP), Recombinant Protein - MBS1418136 from MyBioSource
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Recombinant Mouse Hip Protein - 1568-HP from Novus Biologicals
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Recombinant Human Hip Protein, CF - 9280-HP from Novus Biologicals
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