HHIP

Gene Symbol HHIP
Entrez Gene 64399
Alt Symbol HIP
Species Human
Gene Type protein-coding
Description hedgehog interacting protein
Other Description hedgehog-interacting protein
Swissprots Q9H7E7 Q6PK09 Q9BXK3 Q8NCI7 Q9H1J4 Q96QV1
Accessions AAK18182 CAK96038 CBI67672 EAX05054 Q96QV1 AK024645 BAB14945 AK074711 BAC11154 AK098525 AK291849 BAF84538 AY009317 AAG35411 AY009951 AAG34731 AY358747 AAQ89107 BC009298 AAH09298 BC015636 BC025311 AAH25311 BI602235 DQ893618 ABM84544 XM_005263178 XP_005263235 XM_006714288 XP_006714351 NM_022475 NP_071920
Function Modulates hedgehog signaling in several cell types including brain and lung through direct interaction with members of the hedgehog family. {ECO:0000269|PubMed:11472839, ECO:0000269|PubMed:19561609}.
Subcellular Location Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Secreted {ECO:0000250}. Note=The last 22 C-terminal amino acids may participate in cell membrane attachment.
Tissue Specificity Widely expressed in fetal and adult tissues. Highest expression in adult heart, liver and pancreas, and in fetal kidney. {ECO:0000269|PubMed:11435703, ECO:0000269|Ref.1}.
Top Pathways Hedgehog signaling pathway, Basal cell carcinoma, cAMP signaling pathway

Human Hhip peptide - ab39947 from Abcam

Category Peptide

Human Hhip protein fragment - ab153485 from Abcam

Category Protein
Source Wheat germ
Species Human
ab153485 on a 12.5% SDS-PAGE stained with Coomassie Blue.

HHIP / HIP Antibody Blocking Peptide - LS-E5527 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human Hip Protein - H00064399-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

HHIP-Antibody-N-term-Blocking-Peptide - BP18055a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

Hedgehog-interacting protein / HHIP - H00064399-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

Hedgehog-interacting protein / HHIP - H00064399-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

HHIP fusion protein - ag2241 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

Recombinant Hedgehog Interacting Protein (HHIP) - RPC524Hu01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Human

Recombinant Hedgehog Interacting Protein (HHIP) - RPC524Mu01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Mouse

Recombinant Hedgehog Interacting Protein (HHIP) - RPC524Mu02 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Mouse

Recombinant Human Hedgehog-interacting protein(HHIP) - CSB-YP850419HU CSB-EP850419HU CSB-BP850419HU CSB-MP850419HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

HHIP Peptide, Human - M34GP06974H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

Recombinant Human Hip Protein, CF - 9280-HP from R&D Systems

Category Protein
Prices $389.00
Sizes 50 µg
Source Chinese Hamster Ovary cell line, CHO-derived Human Hip (Phe18-Asp670) Accession # Q96QV1 HP GGGSGGGSGGGS HHHHHH N-terminus C-terminus
Species Human
Recombinant Human Sonic Hedgehog/Shh (Catalog # 8908-SH) induces alkaline phosphatase production in C3H10T1/2 cells (green line). Recombinant Human Hip (Catalog # 9280-HP) inhibits a constant dose of 20 ng/mL of Recombinant Human Sonic Hedgehog/Shh Protein, High Activity (Catalog # 8908-SH ) in C3H10T1/2 mouse embryonic fibroblasts with an ED 50 = 0.1-0.6 µg/mL (orange line).

Hedgehog-interacting protein (HHIP), Recombinant Protein - MBS1418136 from MyBioSource

Category Protein
Prices $1,485.00, $1,485.00, $1,715.00, $1,715.00, $2,540.00, $2,540.00, $2,980.00, $2,980.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

Recombinant Mouse Hip Protein - 1568-HP from Novus Biologicals

Category Protein
Prices $329.00
Sizes 50 µg

Recombinant Human Hip Protein, CF - 9280-HP from Novus Biologicals

Category Protein
Prices $389.00
Sizes 50 µg
Species Human
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