MPRIP

Gene Symbol	MPRIP
Entrez Gene	23164
Alt Symbol	M-RIP, MRIP, RHOIP3, RIP3, p116Rip
Species	Human
Gene Type	protein-coding
Description	myosin phosphatase Rho interacting protein
Other Description	Rho interacting protein 3|myosin phosphatase Rho-interacting protein
Swissprots	Q6WCQ1 Q6DHW2 Q3KQZ5 Q8N390 Q7Z5Y2 Q5FB94 Q96G40
Accessions	CDI70968 EAW55721 EAW55722 EAW55723 EAW55724 Q6WCQ1 AB020671 BAA74887 AB098507 BAC78198 AB189741 BAD89507 AB362572 BAF81537 AB362573 BAF81538 AJ844625 CAH59751 AK025229 AK025604 AK026035 AK091337 AK092287 BAC03851 AL834513 CAD39169 AY296247 AAQ63176 BC009982 AAH09982 BC012426 AAH12426 BC014102 BC021058 BC021070 BC030255 BC050323 BC063588 BC075847 AAH75847 BC105987 AAI05988 BC136479 AAI36480 BE048871 BU527795 CF126021 D23673 DQ582316 DQ598455 XM_005256563 XP_005256620 XM_005256564 XP_005256621 XM_011523761 XP_011522063 XM_011523762 XP_011522064 XM_011523763 XP_011522065 XM_011523764 XP_011522066 XM_011523765 XP_011522067 XM_011523766 XP_011522068 XM_011523767 XP_011522069 NM_015134 NP_055949 NM_201274 NP_958431
Function	Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F- actin-binding region leads to disassembly of stress fibers in neuronal cells. {ECO:0000250|UniProtKB:P97434, ECO:0000269|PubMed:15545284, ECO:0000269|PubMed:16257966}.
Subcellular Location	Cytoplasm, cytoskeleton {ECO:0000269|PubMed:14506264, ECO:0000269|PubMed:16257966}. Note=Colocalizes with F-actin.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

MPRIP / RIP3 Antibody Blocking Peptide - LS-E21154 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RIP3 Blocking Peptide - 33R-10704 from Fitzgerald Category Peptide Prices $115.00 Sizes 50 µg

p116 Rip Blocking Peptide - CBP3396 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Bovine, Pig

p116 Rip Blocking Peptide - CBP4093 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Bovine, Pig

M-RIP (E785) Peptide - BS9177P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Receptor Interacting Serine Threonine Kinase 3 (RIPK3) - RPE639Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Myosin phosphatase Rho-interacting protein(MPRIP) ,partial - CSB-YP744296HU CSB-EP744296HU CSB-BP744296HU CSB-MP744296HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

MPRIP Recombinant Protein Antigen - NBP1-81036PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

MPRIP Recombinant Protein Antigen - NBP1-81035PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

p116 Rip Blocking Peptide - abx162258 from Abbexa Category Peptide Species Human, Mouse, Rat, Bovine, Pig

p116 Rip Blocking Peptide - abx162586 from Abbexa Category Peptide Species Human, Mouse, Rat, Bovine, Pig

MPRIP Peptide, Human - M34GP09689H from Creative Peptides Category Peptide Source Synthetic. Species Human

Myosin phosphatase Rho-interacting protein (MPRIP), partial, Recombinant Protein - MBS1371432 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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