Gene Symbol | STXBP2 |
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Entrez Gene | 6813 |
Alt Symbol | FHL5, Hunc18b, MUNC18-2, UNC18-2, UNC18B, pp10122 |
Species | Human |
Gene Type | protein-coding |
Description | syntaxin binding protein 2 |
Other Description | protein unc-18 homolog B|syntaxin-binding protein 2|unc-18B |
Swissprots | Q9BU65 Q15833 E7EQD5 B4E175 |
Accessions | EAW69017 EAW69018 Q15833 AB002559 BAA19547 AF318317 AAL55824 AI571535 AK098000 AK222967 BAD96687 AK222977 BAD96697 AK302257 BAG63608 AK303701 BAG64687 AK314230 AU098728 BC002869 AAH02869 BQ067493 BT006915 AAP35561 DA431480 JF432705 ADZ15922 U63533 AAC50762 XM_011528210 XP_011526512 XM_011528211 XP_011526513 XM_011528212 XP_011526514 XM_011528213 XP_011526515 NM_001127396 NP_001120868 NM_001272034 NP_001258963 NM_006949 NP_008880 NR_073560 |
Function | Involved in intracellular vesicle trafficking and vesicle fusion with membranes. Contributes to the granule exocytosis machinery through interaction with soluble N- ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins that regulate membrane fusion. Regulates cytotoxic granule exocytosis in natural killer (NK) cells. {ECO:0000269|PubMed:19804848, ECO:0000269|PubMed:19884660}. |
Tissue Specificity | Placenta, lung, liver, kidney and pancreas, as well as in peripheral blood lymphocytes. |
Unc18-1/2 (N-19) - sc-14560 from Santa Cruz Biotechnology
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Unc18-2 (A-6) - sc-390503 from Santa Cruz Biotechnology
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Unc18-2 (B-2) - sc-376639 from Santa Cruz Biotechnology
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Unc18-2 (C-20) - sc-14563 from Santa Cruz Biotechnology
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Unc18-2 (D-2) - sc-390864 from Santa Cruz Biotechnology
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Unc18-2 (H-40) - sc-366192 from Santa Cruz Biotechnology
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Unc18-2 (I-14) - sc-23014 from Santa Cruz Biotechnology
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Anti-STXBP2 antibody - ab123679 from Abcam
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Anti-STXBP2 antibody - C-terminal - ab197798 from Abcam
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Anti-STXBP2 Antibody (aa439-469) - LS-C161598 from LifeSpan Bioscience
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Anti-STXBP2 Antibody (aa101-371) - LS-C185522 from LifeSpan Bioscience
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Anti-STXBP2 Antibody (aa58-70) IHC-plus™ - LS-B2356 from LifeSpan Bioscience
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Anti-STXBP2 Antibody (aa58-70) - LS-C25382 from LifeSpan Bioscience
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Anti-STXBP2 Antibody (aa81-223) - LS-C130625 from LifeSpan Bioscience
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Anti-STXBP2 Antibody (aa439-469, AP) - LS-C270643 from LifeSpan Bioscience
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Anti-STXBP2 Antibody (aa439-469, APC) - LS-C270644 from LifeSpan Bioscience
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Anti-STXBP2 Antibody (aa439-469, Biotin) - LS-C270645 from LifeSpan Bioscience
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Anti-STXBP2 Antibody (aa439-469, FITC) - LS-C270646 from LifeSpan Bioscience
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Anti-STXBP2 Antibody (aa439-469, Azide-free, HRP) - LS-C270647 from LifeSpan Bioscience
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Anti-STXBP2 Antibody (aa439-469, PE) - LS-C270648 from LifeSpan Bioscience
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Anti-STXBP2 Antibody (aa439-469) - LS-C325483 from LifeSpan Bioscience
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Syntaxin-BP2 Antibody - AF5900 from Novus Biologicals
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Syntaxin-BP2 Antibody - NBP2-20527 from Novus Biologicals
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Syntaxin-BP2 Antibody - NBP1-33306 from Novus Biologicals
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Syntaxin-BP2 Antibody - NBP1-83137 from Novus Biologicals
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