| Gene Symbol |
STXBP2
|
| Entrez Gene |
6813
|
| Alt Symbol |
FHL5, Hunc18b, MUNC18-2, UNC18-2, UNC18B, pp10122
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
syntaxin binding protein 2
|
| Other Description |
protein unc-18 homolog B|syntaxin-binding protein 2|unc-18B
|
| Swissprots |
Q9BU65 Q15833 E7EQD5 B4E175
|
| Accessions |
EAW69017 EAW69018 Q15833 AB002559 BAA19547 AF318317 AAL55824 AI571535 AK098000 AK222967 BAD96687 AK222977 BAD96697 AK302257 BAG63608 AK303701 BAG64687 AK314230 AU098728 BC002869 AAH02869 BQ067493 BT006915 AAP35561 DA431480 JF432705 ADZ15922 U63533 AAC50762 XM_011528210 XP_011526512 XM_011528211 XP_011526513 XM_011528212 XP_011526514 XM_011528213 XP_011526515 NM_001127396 NP_001120868 NM_001272034 NP_001258963 NM_006949 NP_008880 NR_073560
|
| Function |
Involved in intracellular vesicle trafficking and vesicle fusion with membranes. Contributes to the granule exocytosis machinery through interaction with soluble N- ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins that regulate membrane fusion. Regulates cytotoxic granule exocytosis in natural killer (NK) cells. {ECO:0000269|PubMed:19804848, ECO:0000269|PubMed:19884660}.
|
| Tissue Specificity |
Placenta, lung, liver, kidney and pancreas, as well as in peripheral blood lymphocytes.
|