Gene Symbol | STXBP2 |
---|---|
Entrez Gene | 6813 |
Alt Symbol | FHL5, Hunc18b, MUNC18-2, UNC18-2, UNC18B, pp10122 |
Species | Human |
Gene Type | protein-coding |
Description | syntaxin binding protein 2 |
Other Description | protein unc-18 homolog B|syntaxin-binding protein 2|unc-18B |
Swissprots | Q9BU65 Q15833 E7EQD5 B4E175 |
Accessions | EAW69017 EAW69018 Q15833 AB002559 BAA19547 AF318317 AAL55824 AI571535 AK098000 AK222967 BAD96687 AK222977 BAD96697 AK302257 BAG63608 AK303701 BAG64687 AK314230 AU098728 BC002869 AAH02869 BQ067493 BT006915 AAP35561 DA431480 JF432705 ADZ15922 U63533 AAC50762 XM_011528210 XP_011526512 XM_011528211 XP_011526513 XM_011528212 XP_011526514 XM_011528213 XP_011526515 NM_001127396 NP_001120868 NM_001272034 NP_001258963 NM_006949 NP_008880 NR_073560 |
Function | Involved in intracellular vesicle trafficking and vesicle fusion with membranes. Contributes to the granule exocytosis machinery through interaction with soluble N- ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins that regulate membrane fusion. Regulates cytotoxic granule exocytosis in natural killer (NK) cells. {ECO:0000269|PubMed:19804848, ECO:0000269|PubMed:19884660}. |
Tissue Specificity | Placenta, lung, liver, kidney and pancreas, as well as in peripheral blood lymphocytes. |
Unc18-2 CRISPR/Cas9 KO Plasmid (h) - sc-403691 from Santa Cruz Biotechnology
|
||||||||
Unc18-2 HDR Plasmid (h) - sc-403691-HDR from Santa Cruz Biotechnology
|
||||||||
Unc18-2 Double Nickase Plasmid (h) - sc-403691-NIC from Santa Cruz Biotechnology
|
||||||||
Unc18-2 Double Nickase Plasmid (h2) - sc-403691-NIC-2 from Santa Cruz Biotechnology
|
||||||||
Unc18-2 CRISPR Activation Plasmid (h) - sc-403691-ACT from Santa Cruz Biotechnology
|
||||||||
Unc18-2 CRISPR Activation Plasmid (h2) - sc-403691-ACT-2 from Santa Cruz Biotechnology
|
||||||||
Unc18-2 Lentiviral Activation Particles (h) - sc-403691-LAC from Santa Cruz Biotechnology
|
||||||||
Unc18-2 Lentiviral Activation Particles (h2) - sc-403691-LAC-2 from Santa Cruz Biotechnology
|
||||||||
Unc18-2 siRNA (h) - sc-42310 from Santa Cruz Biotechnology
|
||||||||
Unc18-2 shRNA Plasmid (h) - sc-42310-SH from Santa Cruz Biotechnology
|
||||||||
Unc18-2 shRNA (h) Lentiviral Particles - sc-42310-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU100441 from Sigma-Aldrich
|
||||||||
MISSION® esiRNA - EHU088811 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN20792 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20792 from Sigma-Aldrich
|
||||||||
STXBP2 siRNA (Human) - CRH4658 from Cohesion Biosciences
|
||||||||
STXBP2 - MBS8239308 from MyBioSource
|
||||||||
shRNA set against Human STXBP2 (NM_006949.2) - SHH420444 from Creative biogene
|
||||||||
Human STXBP2 siRNA - orb265160 from Biorbyt
|
||||||||
STXBP2 shRNA Plasmid (Human) - CHH4658 from Cohesion Biosciences
|
||||||||
STXBP2 miRNA 3'UTR clone - MiUTR3H-04343 from Creative biogene
|
||||||||
STXBP2 miRNA 3'UTR clone - MiUTR3H-04344 from Creative biogene
|