| Gene Symbol |
RGS16
|
| Entrez Gene |
6004
|
| Alt Symbol |
A28-RGS14, A28-RGS14P, RGS-R
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
regulator of G-protein signaling 16
|
| Other Description |
hRGS-r|regulator of G-protein signalling 16|retinal-specific RGS|retinally abundant regulator of G-protein signaling
|
| Swissprots |
Q99701 B2R4M4 O15492 Q5VYN9
|
| Accessions |
AAC39642 CBX47530 EAW91129 O15492 AF493937 AAM12651 AK301261 BAG62827 AK311880 BAG34821 AW193671 BC006243 AAH06243 BT006638 AAP35284 DA060276 DC349953 U70426 AAC16912 U94829 AAC52040 NM_002928 NP_002919
|
| Function |
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha. May play a role in regulating the kinetics of signaling in the phototransduction cascade.
|
| Tissue Specificity |
Abundantly expressed in retina with lower levels of expression in most other tissues.
|