Gene Symbol | RGS16 |
---|---|
Entrez Gene | 6004 |
Alt Symbol | A28-RGS14, A28-RGS14P, RGS-R |
Species | Human |
Gene Type | protein-coding |
Description | regulator of G-protein signaling 16 |
Other Description | hRGS-r|regulator of G-protein signalling 16|retinal-specific RGS|retinally abundant regulator of G-protein signaling |
Swissprots | Q99701 B2R4M4 O15492 Q5VYN9 |
Accessions | AAC39642 CBX47530 EAW91129 O15492 AF493937 AAM12651 AK301261 BAG62827 AK311880 BAG34821 AW193671 BC006243 AAH06243 BT006638 AAP35284 DA060276 DC349953 U70426 AAC16912 U94829 AAC52040 NM_002928 NP_002919 |
Function | Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha. May play a role in regulating the kinetics of signaling in the phototransduction cascade. |
Tissue Specificity | Abundantly expressed in retina with lower levels of expression in most other tissues. |