Gene Symbol | RGS16 |
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Entrez Gene | 6004 |
Alt Symbol | A28-RGS14, A28-RGS14P, RGS-R |
Species | Human |
Gene Type | protein-coding |
Description | regulator of G-protein signaling 16 |
Other Description | hRGS-r|regulator of G-protein signalling 16|retinal-specific RGS|retinally abundant regulator of G-protein signaling |
Swissprots | Q99701 B2R4M4 O15492 Q5VYN9 |
Accessions | AAC39642 CBX47530 EAW91129 O15492 AF493937 AAM12651 AK301261 BAG62827 AK311880 BAG34821 AW193671 BC006243 AAH06243 BT006638 AAP35284 DA060276 DC349953 U70426 AAC16912 U94829 AAC52040 NM_002928 NP_002919 |
Function | Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha. May play a role in regulating the kinetics of signaling in the phototransduction cascade. |
Tissue Specificity | Abundantly expressed in retina with lower levels of expression in most other tissues. |
RGS16 CRISPR/Cas9 KO Plasmid (h) - sc-403744 from Santa Cruz Biotechnology
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RGS16 HDR Plasmid (h) - sc-403744-HDR from Santa Cruz Biotechnology
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RGS16 Double Nickase Plasmid (h) - sc-403744-NIC from Santa Cruz Biotechnology
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RGS16 Double Nickase Plasmid (h2) - sc-403744-NIC-2 from Santa Cruz Biotechnology
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RGS16 CRISPR Activation Plasmid (h) - sc-403744-ACT from Santa Cruz Biotechnology
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RGS16 CRISPR Activation Plasmid (h2) - sc-403744-ACT-2 from Santa Cruz Biotechnology
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RGS16 Lentiviral Activation Particles (h) - sc-403744-LAC from Santa Cruz Biotechnology
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RGS16 Lentiviral Activation Particles (h2) - sc-403744-LAC-2 from Santa Cruz Biotechnology
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RGS16 siRNA (h) - sc-37161 from Santa Cruz Biotechnology
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RGS16 shRNA Plasmid (h) - sc-37161-SH from Santa Cruz Biotechnology
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RGS16 shRNA (h) Lentiviral Particles - sc-37161-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU138261 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN18220 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18220 from Sigma-Aldrich
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RGS16 siRNA (Human) - CRH4072 from Cohesion Biosciences
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RGS16 RNAi - H00006004-R01 from Novus Biologicals
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RGS16 - MBS8212296 from MyBioSource
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shRNA set against Human RGS16 (NM_002928.3) - SHH394876 from Creative biogene
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shRNA set against Human RGS16(NM_002928.3) - SHR178944 from Creative biogene
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Human RGS16 siRNA - orb264574 from Biorbyt
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RGS16 shRNA Plasmid (Human) - CHH4072 from Cohesion Biosciences
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RGS16 miRNA 3'UTR clone - MiUTR1H-08785 from Creative biogene
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