ELAC2

Gene Symbol ELAC2
Entrez Gene 60528
Alt Symbol COXPD17, ELC2, HPC2
Species Human
Gene Type protein-coding
Description elaC ribonuclease Z 2
Other Description RNase Z 2|elaC homolog 2|elaC homolog protein 2|heredity prostate cancer protein 2|putative prostate cancer susceptibility protein HPC2/ELAC2|ribonuclease Z 2|tRNA 3 endonuclease 2|tRNase Z (long form)|tRNase Z 2|zinc phosphodiesterase ELAC protein 2
Swissprots Q9NVT1 Q9BQ52 Q9HAS8 Q6IA94 B4DPL9 Q9HAS9
Accessions AAG24439 AAG24440 EAW89961 EAW89962 EAW89963 EAW89964 Q9BQ52 AA706335 AF304370 AAG24441 AK001392 AK074244 AK094012 AK094333 BAG52861 AK094687 BAG52912 AK124838 BAC85964 AK125030 BAC86026 AK298397 BAG60631 AK300011 BAG61827 AK304589 BAG65377 BC001939 AAH01939 BC004158 AAH04158 BC046924 CB241821 CR457261 CAG33542 DB455960 DC394013 DC411088 JF432300 ADZ15517 NM_001165962 NP_001159434 NM_018127 NP_060597 NM_173717 NP_776065
Function Zinc phosphodiesterase, which displays mitochondrial tRNA 3'-processing endonuclease activity. Involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA. {ECO:0000269|PubMed:21593607}.
Subcellular Location Mitochondrion {ECO:0000269|PubMed:21593607}. Nucleus {ECO:0000269|PubMed:21593607}. Note=Mainly mitochondrial.
Tissue Specificity Widely expressed. Highly expressed in heart, placenta, liver, skeletal muscle, kidney, pancreas, testis and ovary. Weakly expressed in brain, lung, spleen, thymus, prostate, small intestine, colon and leukocytes. {ECO:0000269|PubMed:11175785}.
Top Pathways RNA transport

ELAC2 (E-13) - sc-138773 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

ELAC2 (K-15) - sc-138774 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
ELAC2 (K-15): sc-138774. Western blot analysis of ELAC2 expression in COLO320DM (A), HEK293 (B) and MCF7 (C) whole cell lysates.

ELAC2 (T-15) - sc-138775 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-ELAC2 antibody - ab72636 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-ELAC2 antibody (ab72636) at 1/500 dilution + COLO 320 HSR cell lysateSecondaryHRP-conjugated goat anti-mouse IgG at 1/2500 dilution

Anti-ELAC2 antibody - ab103793 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-ELAC2 antibody (ab103793) at 5 µg/ml + Human liver tissue lysate at 50 µg

Anti-ELAC2 antibody - ab110953 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry analysis of paraffin-embedded Human brain tissue, using a/50 ab111953. The picture on the right is treated with the synthesized peptide

Anti-ELAC2 antibody - C-terminal - ab197944 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-ELAC2 antibody - C-terminal (ab197944) at 1/250 dilutionLane 1 : Lovo cell lysateLane 2 : Hela cell lysateLysates/proteins at 40 µg per lane.

Anti-ELAC2 Antibody (aa2-101) - LS-C307382 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-ELAC2 Antibody - LS-C307381 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-ELAC2 Antibody - LS-C310235 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ELAC2 Antibody - LS-C346390 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence blot of A549 cell using ELAC2 antibody. Blue: DAPI for nuclear staining.

Anti-ELAC2 Antibody (aa345-394) - LS-C201394 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of Human HepG2. ELAC2 antibody dilution 1.0 ug/ml.

Anti-ELAC2 Antibody (aa161-210) IHC-plus™ - LS-B5670 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-ELAC2 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5670 concentration 10 ug/ml.

ELAC2 Antibody - NBP1-84620 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ELAC2 Antibody [NBP1-84620] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp

ELAC2 Antibody - H00060528-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

ELAC2 Antibody (1A2) - H00060528-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1A2
Immunocytochemistry/Immunofluorescence: ELAC2 Antibody (1A2) [H00060528-M01] - Analysis of monoclonal antibody to ELAC2 on HeLa cell. Antibody concentration 10 ug/ml.

ELAC2 Antibody - H00060528-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: ELAC2 Antibody [H00060528-B01P] - Analysis of ELAC2 expression in Jurkat.

ELAC2 Antibody - NBP1-31871 from Novus Biologicals

Host Rabbit
Clonality Polyclonal

ELAC2 Antibody - H00060528-D01 from Novus Biologicals

Prices $399.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ELAC2 Polyclonal Antibody - bs-4276R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Antigen: bs-4276P, 0.2ug/100ul \\nPrimary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000; \\nSecondary: HRP conjugated Goat-Anti-Rabbit IgG(bs-0295G-HRP) at 1: 5000;\\nTMB staining;\\nRead the data in MicroplateReader by 450

Anti-ELAC2 antibody produced in mouse - SAB1401791 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Polyclonal Anti-ELAC2, antibody produced in mouse, purified immunoglobulin: <B>Cat. No. SAB1401791</B>: Antibody concentration: 10 μg/mL using HepG2 cell.

Anti-ELAC2 antibody produced in rabbit - SAB1401792 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Polyclonal Anti-ELAC2, antibody produced in rabbit, purified immunoglobulin: <B>Cat. No. SAB1401792</B>: Antibody concentration: 1.0 - 5.0 μg/mL. Specific band of ~92.22 kDa using human liver lysate.

Monoclonal Anti-ELAC2 antibody produced in mouse - SAB1402616 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1A2
<B>Immunofluorescence</B><BR/>Monoclonal Anti-ELAC2, antibody produced in mouse, clone 1A2, purified immunoglobulin: <B>Cat. No. SAB1402616</B>: Antibody concentration: 10 μg/mL using HeLa cell.

ELAC2 Antibody - C-terminal region (ARP41346_P050) - ARP41346_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ELAC2 antibody [N1N3] - GTX105599 from GeneTex

Host Rabbit
Clonality Polyclonal
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