WDR5

Gene Symbol WDR5
Entrez Gene 11091
Alt Symbol BIG-3, CFAP89, SWD3
Species Human
Gene Type protein-coding
Description WD repeat domain 5
Other Description BMP2-induced 3-kb gene protein|SWD3, Set1c WD40 repeat protein, homolog|WD repeat-containing protein 5|WD-repeat protein 5|cilia and flagella associated protein 89
Swissprots P61964
Accessions CAD34861 EAW88117 EAW88118 EAW88119 EAW88120 P61964 AA490313 AJ011376 CAB66159 AK000552 BAA91248 AK024484 BAB15774 AK025810 BC001635 AAH01635 BC015594 BC029769 BG773451 HQ448239 ADQ32719 XM_005272163 XP_005272220 NM_017588 NP_060058 NM_052821 NP_438172
Function Contributes to histone modification. May position the N- terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation. {ECO:0000269|PubMed:16600877, ECO:0000269|PubMed:16829960, ECO:0000269|PubMed:19103755, ECO:0000269|PubMed:19556245, ECO:0000269|PubMed:20018852}.
Subcellular Location Nucleus {ECO:0000269|PubMed:17355966, ECO:0000269|PubMed:20018852}.

Human WDR5 full length protein - ab98079 from Abcam

Category Protein
Source E. coli
Species Human
15% SDS-PAGE analysis of 3µg ab98079

Human WDR5 full length protein - ab198462 from Abcam

Category Protein
Species Human
4-20% SDS-PAGE analysis of ab198462 with Coomassie staining. Lane 1: 1.2 µg ab198462 Lane 2: Protein marker

Human WDR5 full length protein - ab117194 from Abcam

Category Protein
Source E. coli
Species Human

Human WDR5 peptide - ab24388 from Abcam

Category Peptide

WDR5 Antibody Blocking Peptide - LS-E3928 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

WDR5 Antibody Blocking Peptide - LS-E15192 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

WDR5 Antibody Blocking Peptide - LS-E15193 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

WDR5 Antibody Blocking Peptide - LS-E31266 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 50 µg

WDR5 Recombinant Protein - H00011091-P01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

WDR5 Partial Recombinant Protein - H00011091-Q01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

Recombinant Human WDR5 Protein - NBP1-50848 from Novus Biologicals

Category Protein
Prices $269.00, $729.00
Sizes 100 µg, 500 µg
Source E.coli
Species Human

WDR5-Antibody-N-term-Blocking-Peptide - BP16126a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

WDR5 Protein (OPPA02395) - OPPA02395 from Aviva Systems Biology

Category Protein
Prices $100.00
Sizes 5 µg
Source E. Coli

Human WDR5 protein - orb244629 from Biorbyt

Category Protein
Prices $340.00, $629.00, $1,003.00, $1,556.00
Sizes 50 μg, 200 μg, 500 μg, 1 mg
Species Human

Human WDR5 protein - orb81474 from Biorbyt

Category Protein
Prices $170.00, $289.00
Sizes 5 μg, 20 μg
Species Human

WDR5 Blocking Peptide - 33R-4768 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

WDR5 protein (His tag) - 80R-1394 from Fitzgerald

Category Protein
Prices $255.00
Sizes 100 µg
Source E.coli

WDR5 / BIG3 (1-334, His-tag) - AR09569PU-L from Acris Antibodies

Category Protein
Prices $790.00
Sizes 500 µg
Source E. coli
Species Human
WDR5 / BIG3

WDR5 / BIG3 (1-334, His-tag) - AR09569PU-N from Acris Antibodies

Category Protein
Prices $340.00
Sizes 100 µg
Source E. coli
Species Human
WDR5 / BIG3

WDR5 / BIG3 - H00011091-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

WDR5 / BIG3 - H00011091-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

WDR5 / BIG3 - H00011091-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

WDR5 / BIG3 - H00011091-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

WDR5 / BIG3 control peptide - AP10373CP-N from Acris Antibodies

Category Peptide
Prices $235.00
Sizes 100 µg

WDR5 / BIG3 (N-term) Control Peptide - AP55430CP-N from Acris Antibodies

Category Peptide
Prices $135.00
Sizes 50 µg
Western blot analysis of WDR5 in 293 cell lysate with WDR5 antibody AP55430PU-N at 1 µg/ml in (A) the absence and (B) the presence of blocking peptide.
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