WDR5

Gene Symbol	WDR5
Entrez Gene	11091
Alt Symbol	BIG-3, CFAP89, SWD3
Species	Human
Gene Type	protein-coding
Description	WD repeat domain 5
Other Description	BMP2-induced 3-kb gene protein|SWD3, Set1c WD40 repeat protein, homolog|WD repeat-containing protein 5|WD-repeat protein 5|cilia and flagella associated protein 89
Swissprots	P61964
Accessions	CAD34861 EAW88117 EAW88118 EAW88119 EAW88120 P61964 AA490313 AJ011376 CAB66159 AK000552 BAA91248 AK024484 BAB15774 AK025810 BC001635 AAH01635 BC015594 BC029769 BG773451 HQ448239 ADQ32719 XM_005272163 XP_005272220 NM_017588 NP_060058 NM_052821 NP_438172
Function	Contributes to histone modification. May position the N- terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation. {ECO:0000269|PubMed:16600877, ECO:0000269|PubMed:16829960, ECO:0000269|PubMed:19103755, ECO:0000269|PubMed:19556245, ECO:0000269|PubMed:20018852}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:17355966, ECO:0000269|PubMed:20018852}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

WDR5 CRISPR/Cas9 KO Plasmid (h) - sc-402425 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

WDR5 HDR Plasmid (h) - sc-402425-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

WDR5 Double Nickase Plasmid (h) - sc-402425-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

WDR5 Double Nickase Plasmid (h2) - sc-402425-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

WDR5 CRISPR Activation Plasmid (h) - sc-402425-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

WDR5 CRISPR Activation Plasmid (h2) - sc-402425-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

WDR5 Lentiviral Activation Particles (h) - sc-402425-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

WDR5 Lentiviral Activation Particles (h2) - sc-402425-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

WDR5 siRNA (h) - sc-61798 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

WDR5 shRNA Plasmid (h) - sc-61798-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

WDR5 shRNA (h) Lentiviral Particles - sc-61798-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

WDR5 RNAi - H00011091-R02 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

WDR5 RNAi - H00011091-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU109741 from Sigma-Aldrich Category siRNA Prices $250.00 Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN22834 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22834 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR12810 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr12810

WDR5 siRNA (Human) - CRH7583 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

WDR5 - MBS8234710 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human WDR5 (NM_017588.2) - SHH446260 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human WDR5(NM_017588.2) - SHL131638 from Creative biogene Category siRNA Species Reactivities Human

Human WDR5 siRNA - orb268085 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

WDR5 shRNA Plasmid (Human) - CHH7583 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

WDR5 miRNA 3'UTR clone - MiUTR1H-11221 from Creative biogene Species Reactivities Human

WDR5 miRNA 3'UTR clone - MiUTR3H-10361 from Creative biogene Species Reactivities Human

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