CNTN6

Gene Symbol CNTN6
Entrez Gene 27255
Alt Symbol NB3
Species Human
Gene Type protein-coding
Description contactin 6
Other Description contactin-6|neural adhesion molecule|neural recognition molecule NB-3
Swissprots Q9UQ52 Q2KHM2
Accessions CCO13711 EAW63871 EAW63872 Q9UQ52 AB003592 BAA82612 AK125798 AK294786 BAG57911 AK307814 AK314220 BC036338 BC113118 AAI13119 CN364480 DA094373 DA117077 DB170583 HG495391 XM_005265058 XP_005265115 XM_011533589 XP_011531891 XM_011533590 XP_011531892 XM_011533591 XP_011531893 XR_940415 NM_001289080 NP_001276009 NM_001289081 NP_001276010 NM_014461 NP_055276
Function Contactins mediate cell surface interactions during nervous system development. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Involved in motor coordination (By similarity). {ECO:0000250}.
Subcellular Location Cell membrane {ECO:0000250}; Lipid-anchor, GPI-anchor {ECO:0000250}.
Tissue Specificity Expressed in nervous system. Highly expressed in cerebellum. Expressed at intermediate level in thalamus, subthalamic nucleus. Weakly expressed in corpus callosum, caudate nucleus and spinal cord.

Human Contactin 6 full length protein - ab109345 from Abcam

Category Protein
Source HEK 293 cells
Species Human
Induction of Hes-1 with the treatment of hContactin-6-Fc. A Mouse preadpipocyte cell line, 3T3L1, was stimulated with 5 µg/ml of ab109345 as in indicated time points and each cell lysate was prepared and subjected to Western blot by using anti-Mouse Hes-1 or GAPDH (loading control). Lane M: Marker Lane 1: ab109345, 0 minutes Lane 2: ab109345, 10 minutes Lane 3: ab109345, 30 minutes Lane 4: ab109345, 1 h Lane 5: ab109345, 2 h Lane 6: ab109345, 4 h Lane 7: ab109345, 8 h Lane 8: ab109345, 24 h

Recombinant Human Contactin-6 Fc Chimera, CF - 7394-CN-050 from R&D Systems

Category Protein
Source Chinese Hamster Ovary cell line, CHO-derived

NB-3 fusion protein - ag17412 from Proteintech Group

Category Protein
Source E. coli-derived, PET28a
Species Human

NB-3 fusion protein - ag16148 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

Recombinant Human CNTN6, Fc-tagged - CNTN6-26744TH from Creative Biomart

Category Protein
Source HEK 293 cells

Recombinant Contactin 6 (CNTN6) - RPQ114Mu01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Mouse

Contactin-6 - pro10212 from Covalab

Category Protein
Source HEK 293 cells
Species Human

Recombinant Human Contactin-6(CNTN6) ,partial - CSB-YP891801HU CSB-EP891801HU CSB-BP891801HU CSB-MP891801HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

Human Contactin 6 peptide - ab204908 from Abcam

Category Peptide
Species Human

Recombinant Human Contactin-6 Fc Chimera Protein, CF - 7394-CN from R&D Systems

Category Protein
Prices $329.00
Sizes 50 µg
Source Chinese Hamster Ovary cell line, CHO-derived Human Contactin-6 (Asp20-Ser891) Accession # Q9UQ52 IEGRMD Human IgG 1 (Pro100-Lys330) N-terminus C-terminus
Species Human

Contactin-6 Recombinant Protein Antigen - NBP1-91804PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

CNTN6-Antibody-Center-Blocking-Peptide - BP8561c from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

CNTN6 Peptide, Human - M34GP03406H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

Contactin-6 Recombinant Protein - 90-168 from ProSci

Category Protein
Prices $300.00
Sizes 10 µg
Source HEK293 cells
Species Human

Contactin-6 Recombinant Protein - 90-169 from ProSci

Category Protein
Prices $525.00
Sizes 50 µg
Source HEK293 cells
Species Human

Contactin 6, Recombinant Protein - MBS2030316 from MyBioSource

Category Protein
Prices $190.00, $400.00, $620.00
Sizes 10 µg, 50 µg, 100 µg
Source Prokaryotic expression
Species Mouse

Contactin-6 (CNTN6), partial, Recombinant Protein - MBS1356524 from MyBioSource

Category Protein
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

Recombinant Human Contactin-6 Fc Chimera Protein, CF - 7394-CN from Novus Biologicals

Category Protein
Prices $329.00
Sizes 50 µg
Species Human

Recombinant Mouse Contactin-6 Protein, CF - 5890-CN from Novus Biologicals

Category Protein
Prices $329.00
Sizes 50 µg
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