Gene Symbol | CNTN6 |
---|---|
Entrez Gene | 27255 |
Alt Symbol | NB3 |
Species | Human |
Gene Type | protein-coding |
Description | contactin 6 |
Other Description | contactin-6|neural adhesion molecule|neural recognition molecule NB-3 |
Swissprots | Q9UQ52 Q2KHM2 |
Accessions | CCO13711 EAW63871 EAW63872 Q9UQ52 AB003592 BAA82612 AK125798 AK294786 BAG57911 AK307814 AK314220 BC036338 BC113118 AAI13119 CN364480 DA094373 DA117077 DB170583 HG495391 XM_005265058 XP_005265115 XM_011533589 XP_011531891 XM_011533590 XP_011531892 XM_011533591 XP_011531893 XR_940415 NM_001289080 NP_001276009 NM_001289081 NP_001276010 NM_014461 NP_055276 |
Function | Contactins mediate cell surface interactions during nervous system development. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Involved in motor coordination (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000250}; Lipid-anchor, GPI-anchor {ECO:0000250}. |
Tissue Specificity | Expressed in nervous system. Highly expressed in cerebellum. Expressed at intermediate level in thalamus, subthalamic nucleus. Weakly expressed in corpus callosum, caudate nucleus and spinal cord. |
Contactin 6 CRISPR/Cas9 KO Plasmid (h) - sc-409897 from Santa Cruz Biotechnology
|
||||||||
Contactin 6 HDR Plasmid (h) - sc-409897-HDR from Santa Cruz Biotechnology
|
||||||||
Contactin 6 Double Nickase Plasmid (h) - sc-409897-NIC from Santa Cruz Biotechnology
|
||||||||
Contactin 6 Double Nickase Plasmid (h2) - sc-409897-NIC-2 from Santa Cruz Biotechnology
|
||||||||
Contactin 6 CRISPR Activation Plasmid (h) - sc-409897-ACT from Santa Cruz Biotechnology
|
||||||||
Contactin 6 CRISPR Activation Plasmid (h2) - sc-409897-ACT-2 from Santa Cruz Biotechnology
|
||||||||
Contactin 6 Lentiviral Activation Particles (h) - sc-409897-LAC from Santa Cruz Biotechnology
|
||||||||
Contactin 6 Lentiviral Activation Particles (h2) - sc-409897-LAC-2 from Santa Cruz Biotechnology
|
||||||||
Contactin 6 siRNA (h) - sc-43093 from Santa Cruz Biotechnology
|
||||||||
Contactin 6 shRNA Plasmid (h) - sc-43093-SH from Santa Cruz Biotechnology
|
||||||||
Contactin 6 shRNA (h) Lentiviral Particles - sc-43093-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU011911 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN6345 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6345 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR00279 from Sigma-Aldrich
|
||||||||
CNTN6 siRNA (Human) - CRH9047 from Cohesion Biosciences
|
||||||||
CNTN6 - MBS8204673 from MyBioSource
|
||||||||
shRNA set against Human CNTN6 (NM_014461.2) - SHH266729 from Creative biogene
|
||||||||
shRNA set against Human CNTN6(NM_014461.2) - SHG188137 from Creative biogene
|
||||||||
Human CNTN6 siRNA - orb269549 from Biorbyt
|
||||||||
CNTN6 shRNA Plasmid (Human) - CHH9047 from Cohesion Biosciences
|
||||||||
CNTN6 miRNA 3'UTR clone - MiUTR1H-02286 from Creative biogene
|