Gene Symbol |
LCMT2
|
Entrez Gene |
9836
|
Alt Symbol |
PPM2, TYW4
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
leucine carboxyl methyltransferase 2
|
Other Description |
p21WAF1/CIP1 promoter-interacting protein|tRNA wybutosine-synthesizing protein 4|tRNA yW-synthesizing protein 4|tRNA(Phe) (7-(3-amino-3-(methoxycarbonyl)propyl)wyosine(37)-N)-methoxycarbonyltransferase|tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-O)-methyltransferase|tRNA-Wybutosine-synthesizing protein 4|tRNA-yW synthesizing protein 4
|
Swissprots |
O60294 Q96B55 Q9NR10 Q4JFT6
|
Accessions |
AAY88744 O60294 AF265443 AAF75774 AK292587 BAF85276 AK300820 BAG62475 AW505587 BC015949 AAH15949 DB260484 NM_014793 NP_055608
|
Function |
Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA (By similarity). May methylate the carboxyl group of leucine residues to form alpha- leucine ester residues. {ECO:0000250}.
|