Gene Symbol | LCMT2 |
---|---|
Entrez Gene | 9836 |
Alt Symbol | PPM2, TYW4 |
Species | Human |
Gene Type | protein-coding |
Description | leucine carboxyl methyltransferase 2 |
Other Description | p21WAF1/CIP1 promoter-interacting protein|tRNA wybutosine-synthesizing protein 4|tRNA yW-synthesizing protein 4|tRNA(Phe) (7-(3-amino-3-(methoxycarbonyl)propyl)wyosine(37)-N)-methoxycarbonyltransferase|tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-O)-methyltransferase|tRNA-Wybutosine-synthesizing protein 4|tRNA-yW synthesizing protein 4 |
Swissprots | O60294 Q96B55 Q9NR10 Q4JFT6 |
Accessions | AAY88744 O60294 AF265443 AAF75774 AK292587 BAF85276 AK300820 BAG62475 AW505587 BC015949 AAH15949 DB260484 NM_014793 NP_055608 |
Function | Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA (By similarity). May methylate the carboxyl group of leucine residues to form alpha- leucine ester residues. {ECO:0000250}. |