Gene Symbol | LCMT2 |
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Entrez Gene | 9836 |
Alt Symbol | PPM2, TYW4 |
Species | Human |
Gene Type | protein-coding |
Description | leucine carboxyl methyltransferase 2 |
Other Description | p21WAF1/CIP1 promoter-interacting protein|tRNA wybutosine-synthesizing protein 4|tRNA yW-synthesizing protein 4|tRNA(Phe) (7-(3-amino-3-(methoxycarbonyl)propyl)wyosine(37)-N)-methoxycarbonyltransferase|tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-O)-methyltransferase|tRNA-Wybutosine-synthesizing protein 4|tRNA-yW synthesizing protein 4 |
Swissprots | O60294 Q96B55 Q9NR10 Q4JFT6 |
Accessions | AAY88744 O60294 AF265443 AAF75774 AK292587 BAF85276 AK300820 BAG62475 AW505587 BC015949 AAH15949 DB260484 NM_014793 NP_055608 |
Function | Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA (By similarity). May methylate the carboxyl group of leucine residues to form alpha- leucine ester residues. {ECO:0000250}. |
TYW4 CRISPR/Cas9 KO Plasmid (h) - sc-411360 from Santa Cruz Biotechnology
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TYW4 HDR Plasmid (h) - sc-411360-HDR from Santa Cruz Biotechnology
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TYW4 Double Nickase Plasmid (h) - sc-411360-NIC from Santa Cruz Biotechnology
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TYW4 Double Nickase Plasmid (h2) - sc-411360-NIC-2 from Santa Cruz Biotechnology
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TYW4 CRISPR Activation Plasmid (h) - sc-411360-ACT from Santa Cruz Biotechnology
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TYW4 CRISPR Activation Plasmid (h2) - sc-411360-ACT-2 from Santa Cruz Biotechnology
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TYW4 Lentiviral Activation Particles (h) - sc-411360-LAC from Santa Cruz Biotechnology
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TYW4 Lentiviral Activation Particles (h2) - sc-411360-LAC-2 from Santa Cruz Biotechnology
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TYW4 siRNA (h) - sc-90110 from Santa Cruz Biotechnology
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TYW4 shRNA Plasmid (h) - sc-90110-SH from Santa Cruz Biotechnology
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TYW4 shRNA (h) Lentiviral Particles - sc-90110-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU042861 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN11600 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11600 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05469 from Sigma-Aldrich
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LCMT2 siRNA (Human) - CRH6589 from Cohesion Biosciences
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LCMT2 shRNA Plasmid (Human) - CHH6589 from Cohesion Biosciences
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LCMT2 miRNA 3'UTR clone - MiUTR3H-11747 from Creative biogene
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