Gene Symbol | C3AR1 |
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Entrez Gene | 719 |
Alt Symbol | AZ3B, C3AR, HNFAG09 |
Species | Human |
Gene Type | protein-coding |
Description | complement component 3a receptor 1 |
Other Description | C3a anaphylatoxin chemotactic receptor|C3a-R|complement component 3 receptor 1 |
Swissprots | Q16581 O43771 Q92868 |
Accessions | AAP23198 AAR13862 BAC06088 EAW88640 EAW88641 Q16581 AK223388 BAD97108 AK290242 BAF82931 AK312458 BAG35365 BC020742 AAH20742 DQ892004 ABM82930 DQ895197 ABM86123 DQ896840 ABM87839 U28488 AAC50374 U62027 AAC50657 Z73157 CAA97504 NM_004054 NP_004045 |
Function | Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Widely expressed in several differentiated hematopoietic cell lines, in the lung, spleen, ovary, placenta, small intestine, throughout the brain, heart, and endothelial cells. Mostly expressed in lymphoid tissues. |
Top Pathways | Complement and coagulation cascades, Staphylococcus aureus infection, Neuroactive ligand-receptor interaction |
C3aR (D-12) - sc-133172 from Santa Cruz Biotechnology
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C3aR (H-300) - sc-20138 from Santa Cruz Biotechnology
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C3aR (N-15) - sc-14621 from Santa Cruz Biotechnology
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C3aR (17) - sc-53782 from Santa Cruz Biotechnology
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Anti-C3a Receptor antibody - ab126250 from Abcam
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Anti-C3a Receptor antibody - ab103629 from Abcam
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Anti-C3a Receptor antibody - ab7209 from Abcam
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Anti-C3a Receptor antibody [hC3aRZ1] - ab59554 from Abcam
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Anti-C3a Receptor antibody - C-terminal - ab140777 from Abcam
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Anti-C3a Receptor antibody - Extracellular domain - ab140788 from Abcam
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Anti-C3AR / C3a Receptor Antibody (aa161-332) - LS-C20982 from LifeSpan Bioscience
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Anti-C3AR / C3a Receptor Antibody (aa161-332) - LS-C48907 from LifeSpan Bioscience
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Anti-C3AR / C3a Receptor Antibody - LS-C44865 from LifeSpan Bioscience
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Anti-C3AR / C3a Receptor Antibody (clone hC3aRZ1, RPE) - LS-C57959 from LifeSpan Bioscience
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Anti-C3AR / C3a Receptor Antibody (clone 74/rC3aRZ1, FITC) - LS-C62770 from LifeSpan Bioscience
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Anti-C3AR / C3a Receptor Antibody (clone 74/rC3aRZ1, Biotin) - LS-C62769 from LifeSpan Bioscience
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Anti-C3AR / C3a Receptor Antibody (clone 74/rC3aRZ1, PE) - LS-C62771 from LifeSpan Bioscience
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Anti-C3AR / C3a Receptor Antibody - LS-C123299 from LifeSpan Bioscience
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Anti-C3AR / C3a Receptor Antibody (PE) - LS-C128287 from LifeSpan Bioscience
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Anti-C3AR / C3a Receptor Antibody (clone 17) - LS-C140110 from LifeSpan Bioscience
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Anti-C3AR / C3a Receptor Antibody - LS-C123300 from LifeSpan Bioscience
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Anti-C3AR / C3a Receptor Antibody - LS-C127139 from LifeSpan Bioscience
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Anti-C3AR / C3a Receptor Antibody (clone 13A33, FITC) - LS-C182997 from LifeSpan Bioscience
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Anti-C3AR / C3a Receptor Antibody (clone 74/rC3aRZ1) - LS-C34519 from LifeSpan Bioscience
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Anti-C3AR / C3a Receptor Antibody (clone 7/4) - LS-C140177 from LifeSpan Bioscience
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