| Gene Symbol |
C3AR1
|
| Entrez Gene |
719
|
| Alt Symbol |
AZ3B, C3AR, HNFAG09
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
complement component 3a receptor 1
|
| Other Description |
C3a anaphylatoxin chemotactic receptor|C3a-R|complement component 3 receptor 1
|
| Swissprots |
Q16581 O43771 Q92868
|
| Accessions |
AAP23198 AAR13862 BAC06088 EAW88640 EAW88641 Q16581 AK223388 BAD97108 AK290242 BAF82931 AK312458 BAG35365 BC020742 AAH20742 DQ892004 ABM82930 DQ895197 ABM86123 DQ896840 ABM87839 U28488 AAC50374 U62027 AAC50657 Z73157 CAA97504 NM_004054 NP_004045
|
| Function |
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Widely expressed in several differentiated hematopoietic cell lines, in the lung, spleen, ovary, placenta, small intestine, throughout the brain, heart, and endothelial cells. Mostly expressed in lymphoid tissues.
|
| Top Pathways |
Complement and coagulation cascades, Staphylococcus aureus infection, Neuroactive ligand-receptor interaction
|
