RAB8A

Gene Symbol RAB8A
Entrez Gene 4218
Alt Symbol MEL, RAB8
Species Human
Gene Type protein-coding
Description RAB8A, member RAS oncogene family
Other Description mel transforming oncogene (RAB8 homolog)|mel transforming oncogene (derived from cell line NK14)|mel transforming oncogene (derived from cell line NK14)- RAB8 homolog|oncogene c-mel|ras-associated protein RAB8|ras-related protein Rab-8A
Swissprots B4DEK7 P61006 Q6FHV5 P24407
Accessions AAB19681 EAW84526 EAW84527 P61006 AB209767 BAD93004 AF498943 AAM21091 AK025165 AK293676 BAG57118 BC002977 AAH02977 BT007184 AAP35848 BU940750 CR536583 CAG38820 CR542274 CAG47070 DQ892523 ABM83449 DQ895735 ABM86661 X56741 CAA40065 XM_011528020 XP_011526322 NM_005370 NP_005361
Function The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is involved in polarized vesicular trafficking and neurotransmitter release. Together with RAB11A, RAB3IP, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis. Together with MYO5B and RAB11A participates in epithelial cell polarization. Plays an important role in ciliogenesis. Together with MICALL2, may also regulate adherens junction assembly. May play a role in insulin-induced transport to the plasma membrane of the glucose transporter GLUT4 and therefore play a role in glucos
Subcellular Location Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Golgi apparatus. Recycling endosome membrane. Cell projection, cilium. Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle, phagosome membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Colocalizes with OPTN at the Golgi complex and in vesicular structures close to the plasma membrane. In the GDP- bound form, present in the perinuclear region. Shows a polarized distribution to distal regions of cell protrusions in the GTP- bound form. Colocalizes with PARD3, PRKCI, EXOC5, OCLN, PODXL and RAB11A in apical membrane initiation sites (AMIS) during the generation of apical surface and lumenogenesis. Localizes to tubular recycling endosome. Recruited to phagosomes containing S.aureus or M.tuberculosis.
Top Pathways Pancreatic secretion, AMPK signaling pathway

Human RAB8A / RAB8 ELISA Kit (Sandwich ELISA) - LS-F12463 from LifeSpan Bioscience

Category ELISA Kit
Prices $600.00
Sizes 1 plate
Sensitivity 0.156
Range 0.156-10 ng/ml

Ras-related protein Rab-8A (RAB8A), Human, ELISA Kit - E01R0386 from ARP American Research Products

Category ELISA Kit
Prices $535.00, $735.00
Sizes 48 t, 96 t
Sensitivity 0.1ng/ml
Range 0.5-10ng/ml

Ras-related protein Rab-8A, RAB8A, Human, ELISA Kit - E14470h from ARP American Research Products

Category ELISA Kit
Prices $736.00
Sizes 96 t
Range 0.156-10 ng/mL

Ras related protein Rab 8A (RAB8A), ELISA Kit - MBS7236690 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ras-related protein Rab-8A (RAB8A), ELISA Kit - MBS7205672 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ras-related protein Rab-8A (RAB8A), ELISA Kit - MBS7243316 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ras-related protein Rab-8A (RAB8A), ELISA Kit - MBS7232580 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ras-related protein Rab-8A (RAB8A), ELISA Kit - MBS7237966 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ras-related protein Rab-8A (RAB8A), ELISA Kit - MBS7252315 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ras-related protein Rab-8A (RAB8A), ELISA Kit - MBS7222145 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ras-related protein Rab-8A (RAB8A), ELISA Kit - MBS7234436 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ras-related protein Rab-8A (RAB8A), ELISA Kit - MBS7236794 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Ras-related protein Rab-8A (RAB8A), ELISA Kit - MBS7249339 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Mouse RAB8A / RAB8 ELISA Kit (Custom ELISA) - LS-F17309 from LifeSpan Bioscience

Category ELISA Kit
Prices $600.00
Sizes 1 plate
Sensitivity To be determined
Range 0.156-10 ng/ml

Rat RAB8A / RAB8 ELISA Kit (Custom ELISA) - LS-F17308 from LifeSpan Bioscience

Category ELISA Kit
Prices $600.00
Sizes 1 plate
Sensitivity To be determined
Range 0.156-10 ng/ml

Dog RAB8A / RAB8 ELISA Kit (Custom ELISA) - LS-F17311 from LifeSpan Bioscience

Category ELISA Kit
Prices $700.00
Sizes 1 plate
Sensitivity To be determined
Range 0.156-10 ng/ml

Bovine RAB8A / RAB8 ELISA Kit (Custom ELISA) - LS-F17307 from LifeSpan Bioscience

Category ELISA Kit
Prices $700.00
Sizes 1 plate
Sensitivity To be determined
Range 0.156-10 ng/ml

Chicken RAB8A / RAB8 ELISA Kit (Custom ELISA) - LS-F17310 from LifeSpan Bioscience

Category ELISA Kit
Prices $700.00
Sizes 1 plate
Sensitivity To be determined
Range 0.156-10 ng/ml

Ras-related protein Rab-8A, ELISA Kit - MBS288239 from MyBioSource

Category ELISA Kit
Prices $430.00, $570.00, $2,515.00, $4,520.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Range 0.31 ng/ml -20.0 ng/ml.

RAB8A - EKH3230 from Nordic BioSite

Sensitivity 0.094ng/ml
Range 0.156-10ng/ml

RAB8A ELISA Kit (Human) : 96 Wells (OKEH02358) - OKEH02358 from Aviva Systems Biology

Category ELISA Kit
Prices $480.00
Sizes 96 wells
Sensitivity < 0.056 ng/mL
Range 0.156 - 10 ng/mL

Human RAB8A ELISA Kit - E032929 from Biobool

Category ELISA Kit
Sensitivity <0.094ng/ml

Human Ras-related protein Rab-8A ELISA Kit - EK3412 from Signalway Antibody

Category ELISA Kit
Prices $739.00
Sizes 1x96t
Sensitivity less than 0.056ng/ml
Range 0.156-10 ng/mL

anti-RAB8A antibody - ARG64473 from Arigo Biolaboratories

Category ELISA Kit

MEL (Melamine) ELISA Kit - E-FS-E010 from Elabscience

Category ELISA Kit
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