SH3GLB1

Gene Symbol	SH3GLB1
Entrez Gene	51100
Alt Symbol	Bif-1, CGI-61, PPP1R70, dJ612B15.2
Species	Human
Gene Type	protein-coding
Description	SH3-domain GRB2-like endophilin B1
Other Description	Bax-interacting factor 1|SH3 domain-containing GRB2-like protein B1|SH3-containing protein SH3GLB1|endophilin-B1|protein phosphatase 1, regulatory subunit 70
Swissprots	Q9H3Z0 Q5H8U5 Q9NR47 Q9Y371 Q9NYA9 B4E182
Accessions	EAW73181 EAW73182 Q9Y371 AB007960 BAD88797 AF151819 AAD34056 AF257318 AAF81225 AF263293 AAF73017 AF350371 AAK27365 AI936794 AK001954 BAA91999 AK225864 AK303710 BAG64694 BC007455 AAH07455 DB038227 DB451777 DQ893029 ABM83955 DQ896273 ABM87272 XM_006710672 XP_006710735 XM_006710673 XP_006710736 XM_011541538 XP_011539840 NM_001206651 NP_001193580 NM_001206652 NP_001193581 NM_001206653 NP_001193582 NM_016009 NP_057093
Function	May be required for normal outer mitochondrial membrane dynamics. Required for coatomer-mediated retrograde transport in certain cells. May recruit other proteins to membranes with high curvature. May promote membrane fusion. {ECO:0000269|PubMed:11161816, ECO:0000269|PubMed:11604418, ECO:0000269|PubMed:15452144}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:15452144}. Golgi apparatus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Mitochondrion outer membrane {ECO:0000269|PubMed:15452144}; Peripheral membrane protein {ECO:0000269|PubMed:15452144}. Note=Association with the Golgi apparatus depends on the cell type. {ECO:0000250}.
Tissue Specificity	Highly expressed in heart, skeletal muscle, kidney and placenta. Detected at lower levels in brain, colon, thymus, spleen, liver, small intestine, lung and peripheral blood leukocytes. {ECO:0000269|PubMed:11161816, ECO:0000269|PubMed:11259440}.
Top Pathways	Endocytosis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Bif full length protein - ab131821 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

Human Bif full length protein - ab137149 from Abcam Category Protein Prices $345.00 Sizes 100 µg Source E. coli Species Human

Human Bif peptide - ab22809 from Abcam Category Peptide Prices $181.00 Sizes 100 µg Species Human

SH3GLB1 / Bif / Endophilin B1 Antibody Blocking Peptide - LS-E30241 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

SH3GLB1 / Bif / Endophilin B1 Antibody Blocking Peptide - LS-E25240 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SH3GLB1 / Bif / Endophilin B1 Antibody Blocking Peptide - LS-E7457 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SH3GLB1 / Bif / Endophilin B1 Antibody Blocking Peptide - LS-E21545 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SH3GLB1 / Bif / Endophilin B1 Antibody Blocking Peptide - LS-E9443 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Endophilin B1/Bif-1 Protein - H00051100-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human Endophilin B1/Bif-1 Protein - NBP2-23467 from Novus Biologicals Category Protein Prices $269.00 Sizes 100 µg Species Human

Endophilin B1/Bif-1 Peptide - NBP1-76703PEP from Novus Biologicals Category Peptide Prices $149.00 Sizes 50 µg Species Human

Phospho-EndophilinY80-Antibody-Blocking-peptide - BP3682a from Abgent, a WuXi AppTec company Category Peptide Prices $120.00 Sizes 100 µg

Endophilin-B1-Antibody-Y80-Blocking-Peptide - BP8034a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Bif-1 blocking peptide - GTX89961-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat, Bovine

Human SH3GLB1 protein - orb169290 from Biorbyt Category Protein Prices $230.00, $442.00 Sizes 5 μg, 20 μg Source E.coli Species Human

Sh3glb1 Blocking Peptide - 33R-4440 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

SH3GLB1 protein (His tag) - 80R-2579 from Fitzgerald Category Protein Prices $270.00 Sizes 100 µg Source E.coli

Bif Peptide - AC21-0067-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

Endophilin-B1 (1-365, His-tag) - AR50625PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

Endophilin-B1 (1-365, His-tag) - AR50625PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

Endophilin-B1 - H00051100-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Endophilin-B1 - H00051100-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Endophilin-B1 Control Peptide - AP30149CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

SH3GLB1, 1-365aa, Human, His tag, E.coli - 01-P1801 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

Bif Peptide - 3817P from ProSci Category Peptide Species Human

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