SH3GLB1

Gene Symbol SH3GLB1
Entrez Gene 51100
Alt Symbol Bif-1, CGI-61, PPP1R70, dJ612B15.2
Species Human
Gene Type protein-coding
Description SH3-domain GRB2-like endophilin B1
Other Description Bax-interacting factor 1|SH3 domain-containing GRB2-like protein B1|SH3-containing protein SH3GLB1|endophilin-B1|protein phosphatase 1, regulatory subunit 70
Swissprots Q9H3Z0 Q5H8U5 Q9NR47 Q9Y371 Q9NYA9 B4E182
Accessions EAW73181 EAW73182 Q9Y371 AB007960 BAD88797 AF151819 AAD34056 AF257318 AAF81225 AF263293 AAF73017 AF350371 AAK27365 AI936794 AK001954 BAA91999 AK225864 AK303710 BAG64694 BC007455 AAH07455 DB038227 DB451777 DQ893029 ABM83955 DQ896273 ABM87272 XM_006710672 XP_006710735 XM_006710673 XP_006710736 XM_011541538 XP_011539840 NM_001206651 NP_001193580 NM_001206652 NP_001193581 NM_001206653 NP_001193582 NM_016009 NP_057093
Function May be required for normal outer mitochondrial membrane dynamics. Required for coatomer-mediated retrograde transport in certain cells. May recruit other proteins to membranes with high curvature. May promote membrane fusion. {ECO:0000269|PubMed:11161816, ECO:0000269|PubMed:11604418, ECO:0000269|PubMed:15452144}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:15452144}. Golgi apparatus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Mitochondrion outer membrane {ECO:0000269|PubMed:15452144}; Peripheral membrane protein {ECO:0000269|PubMed:15452144}. Note=Association with the Golgi apparatus depends on the cell type. {ECO:0000250}.
Tissue Specificity Highly expressed in heart, skeletal muscle, kidney and placenta. Detected at lower levels in brain, colon, thymus, spleen, liver, small intestine, lung and peripheral blood leukocytes. {ECO:0000269|PubMed:11161816, ECO:0000269|PubMed:11259440}.
Top Pathways Endocytosis

Endophilin B1 CRISPR/Cas9 KO Plasmid (h) - sc-417500 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Endophilin B1 HDR Plasmid (h) - sc-417500-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Endophilin B1 Double Nickase Plasmid (h) - sc-417500-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Endophilin B1 Double Nickase Plasmid (h2) - sc-417500-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Endophilin B1 CRISPR Activation Plasmid (h) - sc-417500-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Endophilin B1 CRISPR Activation Plasmid (h2) - sc-417500-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Endophilin B1 Lentiviral Activation Particles (h) - sc-417500-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Endophilin B1 Lentiviral Activation Particles (h2) - sc-417500-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Endophilin B1 siRNA (h) - sc-63282 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Endophilin B1 shRNA Plasmid (h) - sc-63282-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Endophilin B1 shRNA (h) Lentiviral Particles - sc-63282-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Endophilin B1/Bif-1 RNAi - H00051100-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU098381 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN19273 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19273 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

SH3GLB1 siRNA (Human) - CRH9521 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SH3GLB1 - MBS8212284 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SH3GLB1 (NM_016009.4) - SHH406776 from Creative biogene

Category siRNA
Species Reactivities Human

Human SH3GLB1 siRNA - orb270023 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SH3GLB1 shRNA Plasmid (Human) - CHH9521 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SH3GLB1 miRNA 3'UTR clone - MiUTR4H-TG08035 from Creative biogene

Species Reactivities Human
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