CCBL1

Gene Symbol CCBL1
Entrez Gene 883
Alt Symbol GTK, KAT1, KATI
Species Human
Gene Type protein-coding
Description cysteine conjugate-beta lyase, cytoplasmic
Other Description beta-lysase, kidney|cysteine conjugate-beta lyase; cytoplasmic (glutamine transaminase K, kyneurenine aminotransferase)|cysteine-S-conjugate beta-lyase|glutamine transaminase K|glutamine--phenylpyruvate transaminase|glutamine-phenylpyruvate aminotransferase|kyneurenine aminotransferase|kynurenine aminotransferase I|kynurenine--oxoglutarate transaminase 1|kynurenine--oxoglutarate transaminase I
Swissprots Q16773 Q8N191 Q5T275
Accessions CAB44342 CAB44343 EAW87840 EAW87841 Q16773 AK094505 BAG52878 AK291178 BAF83867 AK297995 BAH12701 AK314427 BAG37043 AU123740 AW073815 BC013069 BC021262 AAH21262 BC022468 BC033685 AAH33685 BI755163 BM692880 BU622726 DA381449 DC413592 EL733697 X82224 CAA57702 XM_006717311 XP_006717374 XM_011519165 XP_011517467 XM_011519166 XP_011517468 XM_011519167 XP_011517469 XM_011519168 XP_011517470 XM_011519169 XP_011517471 XM_011519170 XP_011517472 XR_929870 NM_001122671 NP_001116143 NM_001122672 NP_001116144 NM_001287390 NP_001274319 NM_004059 NP_004050 NR_109829
Function Catalyzes the irreversible transamination of the L- tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Metabolizes the cysteine conjugates of certain halogenated alkenes and alkanes to form reactive metabolites. Catalyzes the beta- elimination of S-conjugates and Se-conjugates of L- (seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond. {ECO:0000269|PubMed:19338303}.
Subcellular Location Cytoplasm.
Top Pathways Chemical carcinogenesis, Selenocompound metabolism, Tryptophan metabolism

KAT I (C-7) - sc-374531 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
KAT I (C-7): sc-374531. Immunofluorescence staining of methanol-fixed HeLa cells showing nucleolar localization.

KAT I (H-5) - sc-166186 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
KAT I (H-5): sc-166186. Western blot analysis of KAT I expression in non-transfected: sc-117752 (A) and mouse KAT I transfected: sc-127032 (B) 293T whole cell lysates.

KAT I (B-8) - sc-271709 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
KAT I (B-8): sc-271709. Western blot analysis of KAT I expression in non-transfected: sc-117752 (A) and mouse KAT I transfected: sc-127032 (B) 293T whole cell lysates.

KAT I (C-16) - sc-54013 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
KAT I (C-16): sc-54013. Western blot analysis of KAT I expression in HeLa whole cell lysate.

KAT I (H-74) - sc-67375 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
KAT I (H-74): sc-67375. Western blot analysis of KAT I expression in HeLa whole cell lysate.

KAT I (N-15) - sc-54015 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
KAT I (N-15): sc-54015. Western blot analysis of KAT I expression in HeLa whole cell lysate.

KAT I (M-59) - sc-67374 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
KAT I (M-59): sc-67374. Western blot analysis of KAT I expression in non-transfected: sc-117752 (A) and mouse KAT I transfected: sc-127032 (B) 293T whole cell lysates.

KAT I (T-16) - sc-54016 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
KAT I (T-16): sc-54016. Western blot analysis of KAT I expression in HeLa whole cell lysate.

Anti-CCBL1 antibody - ab76963 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Anti-CCBL1 antibody (ab76963) at 5 µg/ml + immunogen at 0.2 µgSecondaryGoat anti-mouse IgG (H&L)-HRP conjugate at 1/5000 dilution

Anti-CCBL1 antibody - ab89067 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-CCBL1 antibody (ab89067) at 1 µg/ml + human liver tissue lysate at 50 µg

Anti-CCBL1 antibody - C-terminal - ab174543 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-CCBL1 antibody - C-terminal (ab174543) at 1/100 dilution + MDA-MB453 cell line lysate at 35 µg

Anti-CCBL1 Antibody (clone 1B12) IHC-plus™ - LS-B11727 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 1B12
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)

Anti-CCBL1 Antibody (aa327-355, AP) - LS-C253523 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CCBL1 Antibody (aa343-353) - LS-C54622 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-CCBL1 Antibody (aa327-355, APC) - LS-C253524 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CCBL1 Antibody (aa327-355, Azide-free, HRP) - LS-C253529 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CCBL1 Antibody (aa327-355, Biotin) - LS-C253525 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CCBL1 Antibody (aa327-355, FITC) - LS-C253526 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CCBL1 Antibody (aa327-355, PE) - LS-C253530 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CCBL1 Antibody - LS-C306762 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-CCBL1 Antibody (aa326-355) - LS-C320038 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CCBL1 Antibody (aa327-355) - LS-C159277 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
CCBL1 Antibody western blot of MDA-MB453 cell line lysates (35 ug/lane). The CCBL1 antibody detected the CCBL1 protein (arrow).

Anti-CCBL1 Antibody - LS-C334786 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using CCBL1 antibody.

Cysteine Conjugate beta-Lyase/CCBL1 Antibody - AF7817 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Goat
Clonality Polyclonal
Western blot shows lysates of HeLa human cervical epithelial carcinoma cell line, HepG2 human hepatocellular carcinoma cell line, mouse kidney tissue, and rat kidney tissue. PVDF membrane was probed with 0.5 µg/mL of Goat Anti-Human/Mouse/Rat Cysteine Conjugate beta -Lyase/CCBL1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF7817) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF017). A specific band was detected for Cysteine Conjugate beta -Lyase/CCBL1 at approximately 45 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

Cysteine Conjugate beta-Lyase/CCBL1 Antibody - NBP1-83317 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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