Gene Symbol | CCBL1 |
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Entrez Gene | 883 |
Alt Symbol | GTK, KAT1, KATI |
Species | Human |
Gene Type | protein-coding |
Description | cysteine conjugate-beta lyase, cytoplasmic |
Other Description | beta-lysase, kidney|cysteine conjugate-beta lyase; cytoplasmic (glutamine transaminase K, kyneurenine aminotransferase)|cysteine-S-conjugate beta-lyase|glutamine transaminase K|glutamine--phenylpyruvate transaminase|glutamine-phenylpyruvate aminotransferase|kyneurenine aminotransferase|kynurenine aminotransferase I|kynurenine--oxoglutarate transaminase 1|kynurenine--oxoglutarate transaminase I |
Swissprots | Q16773 Q8N191 Q5T275 |
Accessions | CAB44342 CAB44343 EAW87840 EAW87841 Q16773 AK094505 BAG52878 AK291178 BAF83867 AK297995 BAH12701 AK314427 BAG37043 AU123740 AW073815 BC013069 BC021262 AAH21262 BC022468 BC033685 AAH33685 BI755163 BM692880 BU622726 DA381449 DC413592 EL733697 X82224 CAA57702 XM_006717311 XP_006717374 XM_011519165 XP_011517467 XM_011519166 XP_011517468 XM_011519167 XP_011517469 XM_011519168 XP_011517470 XM_011519169 XP_011517471 XM_011519170 XP_011517472 XR_929870 NM_001122671 NP_001116143 NM_001122672 NP_001116144 NM_001287390 NP_001274319 NM_004059 NP_004050 NR_109829 |
Function | Catalyzes the irreversible transamination of the L- tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Metabolizes the cysteine conjugates of certain halogenated alkenes and alkanes to form reactive metabolites. Catalyzes the beta- elimination of S-conjugates and Se-conjugates of L- (seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond. {ECO:0000269|PubMed:19338303}. |
Subcellular Location | Cytoplasm. |
Top Pathways | Chemical carcinogenesis, Selenocompound metabolism, Tryptophan metabolism |
Human CCBL1 full length protein - ab158038 from Abcam
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Human CCBL1 full length protein - ab158039 from Abcam
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Human CCBL1 full length protein - ab202192 from Abcam
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CCBL1 Antibody Blocking Peptide - LS-E5954 from LifeSpan Bioscience
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CCBL1 Antibody Blocking Peptide - LS-E26574 from LifeSpan Bioscience
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Cysteine Conjugate beta-Lyase/CCBL1 Recombinant Protein - H00000883-P02 from Novus Biologicals
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Cysteine Conjugate beta-Lyase/CCBL1 Recombinant Protein - H00000883-P01 from Novus Biologicals
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CCBL1-Antibody-C-term-Blocking-Peptide - BP18519b from Abgent, a WuXi AppTec company
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CCBL1 blocking peptide - GTX88897-PEP from GeneTex
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CCBL1 Protein Lysate (APL10529) - APL10529 from Aviva Systems Biology
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CCBL1 Protein Lysate (APL10530) - APL10530 from Aviva Systems Biology
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Human CCBL1 protein - orb244805 from Biorbyt
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CCBL1 protein - 80R-4240 from Fitzgerald
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CCBL1 Peptide - AC21-1410-P from Abcore
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CCBL1 (1-422, His-tag) - AR51922PU-N from Acris Antibodies
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CCBL1 (1-422, His-tag) - AR51922PU-S from Acris Antibodies
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CCBL1 - H00000883-P01-02 from Acris Antibodies
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CCBL1 - H00000883-P02 from Acris Antibodies
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CCBL1 - H00000883-P02-10 from Acris Antibodies
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CCBL1 - H00000883-P02-25 from Acris Antibodies
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CCBL1 Peptide - 45-375P from ProSci
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CCBL1 fusion protein - ag2828 from Proteintech Group
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Recombinant Human CCBL1, T7-tagged - CCBL1-387H from Creative Biomart
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Recombinant Human CCBL1, His-tagged - CCBL1-82H from Creative Biomart
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Recombinant Cysteine Conjugate Beta Lyase, Cytoplasmic (CCbL1) - RPD863Hu01 from Uscn Life Science Inc.
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