| Gene Symbol | CCBL1 |
|---|---|
| Entrez Gene | 883 |
| Alt Symbol | GTK, KAT1, KATI |
| Species | Human |
| Gene Type | protein-coding |
| Description | cysteine conjugate-beta lyase, cytoplasmic |
| Other Description | beta-lysase, kidney|cysteine conjugate-beta lyase; cytoplasmic (glutamine transaminase K, kyneurenine aminotransferase)|cysteine-S-conjugate beta-lyase|glutamine transaminase K|glutamine--phenylpyruvate transaminase|glutamine-phenylpyruvate aminotransferase|kyneurenine aminotransferase|kynurenine aminotransferase I|kynurenine--oxoglutarate transaminase 1|kynurenine--oxoglutarate transaminase I |
| Swissprots | Q16773 Q8N191 Q5T275 |
| Accessions | CAB44342 CAB44343 EAW87840 EAW87841 Q16773 AK094505 BAG52878 AK291178 BAF83867 AK297995 BAH12701 AK314427 BAG37043 AU123740 AW073815 BC013069 BC021262 AAH21262 BC022468 BC033685 AAH33685 BI755163 BM692880 BU622726 DA381449 DC413592 EL733697 X82224 CAA57702 XM_006717311 XP_006717374 XM_011519165 XP_011517467 XM_011519166 XP_011517468 XM_011519167 XP_011517469 XM_011519168 XP_011517470 XM_011519169 XP_011517471 XM_011519170 XP_011517472 XR_929870 NM_001122671 NP_001116143 NM_001122672 NP_001116144 NM_001287390 NP_001274319 NM_004059 NP_004050 NR_109829 |
| Function | Catalyzes the irreversible transamination of the L- tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Metabolizes the cysteine conjugates of certain halogenated alkenes and alkanes to form reactive metabolites. Catalyzes the beta- elimination of S-conjugates and Se-conjugates of L- (seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond. {ECO:0000269|PubMed:19338303}. |
| Subcellular Location | Cytoplasm. |
| Top Pathways | Chemical carcinogenesis, Selenocompound metabolism, Tryptophan metabolism |